Adalimumab-Induced Hepatocellular Injury in a Young Male With Hidradenitis Suppurativa and Underlying Metabolically Dysfunctional Liver Disease: A Case Report. [PDF]
Abdulhameed NM +2 more
europepmc +1 more source
Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis +54 more
wiley +1 more source
Hepatobiliary disorders associated with TNF-α inhibitors: a pharmacovigilance analysis of FAERS and JADER. [PDF]
Chen H, Jiang S, Wang J, Zhang A, Zhu L.
europepmc +1 more source
Psoriasis Skin Clearance, Body Mass Index, and Lifestyle Behaviors
International Journal of Dermatology, EarlyView.
Annika Smith +4 more
wiley +1 more source
A meta‐analysis was conducted comparing the efficacy of biologics for the treatment of hidradenitis suppurativa (HS) for 12–16 weeks. Based on the SUCRA, bimekizumab was ranked the most efficacious treatment compared with secukinumab and adalimumab for all assessed efficacy outcomes, positioning it as the best treatment across biologic‐naïve and ...
Haley B. Naik +9 more
wiley +1 more source
The prevalence and potential associations of anti-drug antibodies against adalimumab in patients with non-infectious uveitis: a cross-sectional study. [PDF]
Madhavan A +6 more
europepmc +1 more source
A matching‐adjusted indirect treatment comparison (MAIC) was conducted, comparing approved biologics for long‐term (48–52 weeks) treatment of moderate‐to‐severe hidradenitis suppurativa (HS). Using weighted patient‐level trial data allowed re‐estimation of relative bimekizumab efficacy compared with aggregate secukinumab and adalimumab trial data ...
Thrasyvoulos Tzellos +9 more
wiley +1 more source
Family quality‐of‐life burden in chronic spontaneous urticaria: A multicentre study
Poor control of chronic spontaneous urticaria (CSU) significantly worsens family members' quality of life, especially in emotional, physical, and social domains. Higher disease severity was linked to increased caregiving burden and household expenditures, highlighting the need for family‐centred CSU care and support across diverse global populations ...
Beatrice Martinez Zugaib Abdalla +33 more
wiley +1 more source
Antigen binding triggers long-range conformational changes in monoclonal antibodies. [PDF]
Bianchi D +6 more
europepmc +1 more source
The SKINERGY study will investigate six immune‐mediated inflammatory skin diseases through a nationwide collaboration across all Dutch university medical centres. Involving 720 patients and 120 healthy volunteers, it is aimed at generating a high‐quality dataset to identify biomarkers that enable personalized treatment strategies and improved disease ...
N. G. Koster +68 more
wiley +1 more source

