Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
Overexpression of the transmembrane matrix metalloproteinase MT1-MMP/MMP14 promotes cancer cell invasion. Here we show that MT1-MMP-positive cancer cells turn MT1-MMP-negative cells invasive by transferring a soluble catalytic ectodomain of MT1-MMP ...
Eva Maria Wenzel +9 more
doaj +1 more source
Inactive metallopeptidase homologs: the secret lives of pseudopeptidases
Inactive enzyme homologs, or pseudoenzymes, are proteins, found within most enzyme families, that are incapable of performing catalysis. Rather than catalysis, they are involved in protein-protein interactions, sometimes regulating the activity of their ...
Peter J. Lyons
doaj +1 more source
The role of some ADAM-proteins and activation of the insulin growth factor-related pathway in colorectal cancer. [PDF]
Walkiewicz K +3 more
europepmc +1 more source
Changes in brain white matter structure are associated with urine proteins in urologic chronic pelvic pain syndrome (UCPPS): A MAPP Network study [PDF]
Andriole, Gerald L +10 more
core +2 more sources
ADAM PROTEASE KUZBANIAN CLEAVES MULTIPLE UNRELATED PROTEIN DOMAINS\r
openaire +1 more source
Exosome crown proteins are promising markers for liquid biopsy of breast cancer. [PDF]
Tamkovich S +3 more
europepmc +1 more source
Clinical, Prognostic, and Biological Features of High-Risk Cardiometabolic Phenotype: The REMODEL Study. [PDF]
Muhammad AAR +7 more
europepmc +1 more source
Top-Down Proteomics of Skinned Human Muscle Fibers Reveals Proteoform-Resolved Fiber-to-Fiber Variability. [PDF]
Wilson MC +7 more
europepmc +1 more source
The Acute Effect of Consuming Whey Versus a Plant-Based Protein Blend on Postprandial Metabolism and Appetite in a Sample of Healthy Adults. [PDF]
Petkova YP, Johnston JD, Collins AL.
europepmc +1 more source

