Results 91 to 100 of about 4,756 (186)

ADAMTS1 cleavage of versican mediates essential structural remodeling of the ovarian follicle and cumulus-oocyte matrix during ovulation in mice

, 2010
Remodeling of ovarian follicle extracellular matrix is essential for ovulation and vascularization of the corpus luteum (CL). Formation of the cumulus matrix around oocytes also plays an important role in ovulation and subsequent fertilization of oocytes.
Brown, H., Melanie Pritchard, Michelle Lane, Kylie R. Dunning, Boerboom, D., Derek Boerboom, Lane, M., Hannah M. Brown, Rebecca L. Robker, Dunning, K., Darryl L. Russell, Robker, R., Pritchard, M., Russell, D.   +13 more
core   +1 more source

Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth

eLife, 2020
The umbilical artery lumen closes rapidly at birth, preventing neonatal blood loss, whereas the umbilical vein remains patent longer. Here, analysis of umbilical cords from humans and other mammals identified differential arterial-venous proteoglycan ...
Sumeda Nandadasa, Jason M Szafron, Vai Pathak, Sae-Il Murtada, Caroline M Kraft, Anna O'Donnell, Christian Norvik, Clare Hughes, Bruce Caterson, Miriam S Domowicz, Nancy B Schwartz, Karin Tran-Lundmark, Martina Veigl, David Sedwick, Elliot H Philipson, Jay D Humphrey, Suneel S Apte   +16 more
doaj   +1 more source

ADAMTS1, a putative anti-angiogenic factor, is decreased in human prostate cancer

, 2009
OBJECTIVE: To investigate the expression of 'ADAM metallopeptidase with thrombospondin type I motif, 1' (ADAMTS1) in human prostate cancer, and to study its relationship to microvessel density (MVD) and metastasis.
Damber, Jan-Erik, Gustavsson, Helene,, Damber, Jan-Erik,, Jennbacken, Karin, Welén, Karin, Wang, Wanzhong,, Jennbacken, Karin,, Gustavsson, Heléne, Welén, Karin,   +8 more
core   +1 more source

SP1 and USF differentially regulate ADAMTS1 gene expression under normoxic and hypoxic conditions in hepatoma cells

, 2016
ADAM metallopeptidase with thrombospondin type I motif, 1 (ADAMTS1) that has both antiangiogenic and aggrecanase activity was dysregulated in many pathophysiologic circumstances.
Turkoglu, Sumeyye Aydogan, Kockar, Feray
core   +1 more source

ADAMTS1 is a promoter of metastatic cell behaviour in mammary cancer cells. [PDF]

, 2014
Metastatic disease is the primary cause of mortality in breast cancer. It is characterised by the dissemination of cancer cells from the primary site, infiltration into vessel networks and the establishment of new tumour growth in secondary tissues ...
Tan, Izza Maria Doreen A.
core  

Stroma-derived but not tumor ADAMTS1 is a main driver of tumor growth and metastasis

, 2016
The matrix metalloprotease ADAMTS1 (A Disintegrin And Metalloprotease with ThromboSpondin repeats 1) has been involved in tumorigenesis although its contributions appeared ambiguous.
Carlos Rodriguez-Manzaneque, Juan, Javier Rodriguez-Baena, Francisco, Martino-Echarri, Estefania, Fernandez-Rodriguez, Ruben, Peris-Torres, Carlos, del Carmen Plaza-Calonge, Maria   +5 more
core   +1 more source

Contribución de la proteasa adamts1 en el microentorno tumoral: estudios en un modelo murino de melanoma [PDF]

, 2015
El desarrollo tumoral y la metástasis son dos procesos que están íntimamente ligados al desarrollo de la vasculatura. Al igual que cualquier órgano, los tumores necesitan crear un sistema vascular que colme sus necesidades metabólicas pero para poder ...
Fernández Rodríguez, Rubén
core   +1 more source

In vitro mouse preantral follicle development in 2D and suspension culture: α-MEM vs SAGE 1-step

Reproduction and Fertility
The in vitro culture of immature follicles remains a challenge in reproductive biology, ART, and fertility preservation. This study investigated the impact of α-MEM and SAGE 1-Step media on mouse preantral follicle development and oocyte maturation using
Amir Bazgir, Narges Karami, Fatemeh Hassani, Farah Farokhi, Azam Dalman   +4 more
doaj   +1 more source

Identification of the metalloproteinase Adamts1 and Nitric Oxide as new therapeutic targets in aortic diseases [PDF]

, 2018
Tesis Doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular. Fecha de lectura: 30-06-2017Esta tesis tiene embargado el acceso al texto completo hasta el 30-12-2018El principal origen de las
Oller Pedrosa, Jorge
core   +1 more source

Pre-coculture with breast cancer cells increased ADAMTS1 mRNA levels in NAFs.

, 2012
(A–C) Quantitative real-time RT-PCR analysis revealed that ADAMTS1 mRNA levels were higher in CAFs than in the corresponding NAFs in ten breast cancer patients (A), and that ADAMTS1 mRNA levels in CAF 199C.P10 and NAF 200N.E4.P3 were higher than in NAF ...
Li-Jung Juan (171247), Chih-Hung Hsu (171225), Kai-Lin Peng (171228), Jin-Yuh Shew (171239), Eva Y.-H. P. Lee (171236), King-Jen Chang (132031), Wen-Hwa Lee (171250), Wen-Hung Kuo (132019), Chun-Chin Chen (171232), Shiaw-Wei Tyan (171220)   +9 more
core   +1 more source