Molecular analyses of ADAMTS-1, -4, -5, and IL-17 a cytokine relationship in patients with ulcerative colitis [PDF]
BMC Gastroenterology, 2023 Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease that develops due to the impaired immune response in genetically susceptible individuals, and its etiopathogenesis is not fully elucidated.
Tahir Buran +6 more
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Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma [PDF]
International Journal of Dentistry, 2022 Background. Ameloblastoma is a benign but locally invasive odontogenic epithelial tumor, associated with a high recurrence rate after treatment. The action of enzymes of the metalloproteinase family is important to the degraded extracellular matrix ...
Osvaldo Rodrigues de Souza Neto +4 more
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ADAMTS-1: a novel target gene of an estrogen-induced transcription factor, EGR1, critical for embryo implantation in the mouse uterus [PDF]
Cell & Bioscience, 2021 Background Recently, we demonstrated that estrogen (E2) induces early growth response 1 (Egr1) to mediate its actions on the uterine epithelium by controlling progesterone receptor signaling for successful embryo implantation.
Mira Park +5 more
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The role of serum ADAMTS-1 levels in Hyperemesis Gravidarum [PDF]
BMC Pregnancy and Childbirth, 2022 Background We aimed to investigate the levels of ADAMTS-1, which is secreted from the extracellular matrix during trophoblastic invasion in hyperemesis gravidarum (HEG).
Burcu Timur, Gurhan Guney
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ADAMTS-1 in abdominal aortic aneurysm. [PDF]
PLoS ONE, 2017 Extracellular matrix degradation is a hallmark of abdominal aortic aneurysm (AAA). Among proteases that are capable of degrading extracellular matrix are a disintegrin and metalloproteases with thrombospondin motifs (ADAMTS).
Emina Vorkapic +5 more
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ADAMTS-1, ADAMTS-5 and ADAMTS-13 are considered potential targets in the treatment of frozen shoulder [PDF]
Journal of Orthopaedic Surgery and ResearchBackground Frozen shoulder (FS) is a condition that causes shoulder pain and restricted movement, primarily due to inflammation, fibrosis, and adhesion of the shoulder joint capsule. It commonly affects individuals aged 30 to 60 years.
Zihao Zhou, Guanhong Chen
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ADAMTS-1 Is Found in the Nuclei of Normal and Tumoral Breast Cells. [PDF]
PLoS ONE, 2016 Proteins secreted in the extracellular matrix microenvironment (ECM) by tumor cells are involved in cell adhesion, motility, intercellular communication and invasion.
Suély V Silva +4 more
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Prognostic value of von Willebrand factor and ADAMTS-13 in patients with sepsis-induced coagulopathy [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: The von Willebrand factor (VWF)– a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13 (ADAMTS-13) axis may contribute to microvascular thrombosis and poor outcomes in sepsis-induced coagulopathy (SIC).
Feng Zhang +3 more
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Daratumumab for relapsed refractory immune thrombotic thrombocytopenic purpura: initial response and long-term follow-up [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Management of patients with refractory or frequently relapsing (r/r) immune thrombotic thrombocytopenic purpura (iTTP) remains challenging, with no established consensus on optimal therapeutic strategies.
Roman Schimmer +6 more
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Differential Expression and Localization of ADAMTS Proteinases in Proliferative Diabetic Retinopathy
Molecules, 2022 We analyzed the expression of ADAMTS proteinases ADAMTS-1, -2, -4, -5 and -13; their activating enzyme MMP-15; and the degradation products of proteoglycan substrates versican and biglycan in an ocular microenvironment of proliferative diabetic ...
Ahmed M. Abu El-Asrar +7 more
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