Results 1 to 10 of about 380 (133)

ADAMTS-1 in abdominal aortic aneurysm. [PDF]

PLoS ONE, 2017
Extracellular matrix degradation is a hallmark of abdominal aortic aneurysm (AAA). Among proteases that are capable of degrading extracellular matrix are a disintegrin and metalloproteases with thrombospondin motifs (ADAMTS).
Emina Vorkapic, Maggie Folkesson, Kerstin Magnell, Mohammad Bohlooly-Y, Toste Länne, Dick Wågsäter   +5 more
doaj   +4 more sources

Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma

International Journal of Dentistry, 2022
Background. Ameloblastoma is a benign but locally invasive odontogenic epithelial tumor, associated with a high recurrence rate after treatment. The action of enzymes of the metalloproteinase family is important to the degraded extracellular matrix ...
Osvaldo Rodrigues de Souza Neto, Hellen Thais Fuzii, Suély Vieira Da Silva, Vanessa Morais Freitas, João de Jesus Viana Pinheiro   +4 more
doaj   +3 more sources

Differential Expression and Localization of ADAMTS Proteinases in Proliferative Diabetic Retinopathy

Molecules, 2022
We analyzed the expression of ADAMTS proteinases ADAMTS-1, -2, -4, -5 and -13; their activating enzyme MMP-15; and the degradation products of proteoglycan substrates versican and biglycan in an ocular microenvironment of proliferative diabetic ...
Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Eef Allegaert, Mohammad Mairaj Siddiquei, Ajmal Ahmad, Priscilla Gikandi, Gert De Hertogh, Ghislain Opdenakker   +7 more
doaj   +1 more source

Association of ADAMTS proteoglycanases downregulation with IVF-ET outcomes in patients with polycystic ovary syndrome: a systematic review and meta-analysis

Reproductive Biology and Endocrinology, 2022
Background A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) is involved in inflammation and fertility in women with polycystic ovary syndrome (PCOS).
Yanbin Shi, Yang Shi, Guiyuan He, Guang Wang, Hongbo Liu, Xiaoguang Shao   +5 more
doaj   +1 more source

Molecular analyses of ADAMTS-1, -4, -5, and IL-17 a cytokine relationship in patients with ulcerative colitis

BMC Gastroenterology, 2023
Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease that develops due to the impaired immune response in genetically susceptible individuals, and its etiopathogenesis is not fully elucidated.
Tahir Buran, Muhammet Burak Batır, Fethi Sırrı Çam, Elmas Kasap, Fatih Çöllü, Hamide Betül Gerik Çelebi, Mustafa Şahin   +6 more
doaj   +1 more source

ADAMTS expression in colorectal cancer. [PDF]

PLoS ONE, 2015
ADAMTSs are a family of secreted proteinases that share the metalloproteinase domain with matrix metalloproteinases (MMPs). By acting on a large panel of extracellular substrates, they control several cell functions such as fusion, adhesion ...
Serafula Filou, Aggeliki Korpetinou, Dora Kyriakopoulou, Dimitrios Bounias, Michael Stavropoulos, Panagiota Ravazoula, Dionysios J Papachristou, Achilleas D Theocharis, Demitrios H Vynios   +8 more
doaj   +1 more source

First Characterization of ADAMTS-4 in Kidney Tissue and Plasma of Patients with Chronic Kidney Disease—A Potential Novel Diagnostic Indicator

Diagnostics, 2022
Background: We have previously shown that metzincin protease ADAMTS-4 accompanies renal fibrogenesis, as it appears in the blood of hemodialysis patients.
Ivana Kovacevic Vojtusek, Mario Laganovic, Marija Burek Kamenaric, Stela Bulimbasic, Stela Hrkac, Grgur Salai, Vanja Ivkovic, Marijana Coric, Rudjer Novak, Lovorka Grgurevic   +9 more
doaj   +1 more source

Is There a Role of ADAMTS-1 in Cyst Development in Autosomal Dominant Polycystic Kidney Disease?

Turkish Journal of Nephrology, 2021
Objective: Autosomal dominant polycystic kidney disease (ADPKD) is the most commonly inherited kidney disease. It is characterized by the development of multiple bilateral cysts that cause enlargement of the kidney. The underlying mechanisms related with
Süleyman Karaköse, Pervin Özkan Kurtgöz, Çiğdem Damla Deniz, Edip Erkuş, İbrahim Güney   +4 more
doaj   +1 more source

ADAMTS-1: a novel target gene of an estrogen-induced transcription factor, EGR1, critical for embryo implantation in the mouse uterus

Cell & Bioscience, 2021
Background Recently, we demonstrated that estrogen (E2) induces early growth response 1 (Egr1) to mediate its actions on the uterine epithelium by controlling progesterone receptor signaling for successful embryo implantation.
Mira Park, So Hee Park, Hyunsun Park, Hye-Ryun Kim, Hyunjung J. Lim, Haengseok Song   +5 more
doaj   +1 more source

ADAMTS proteases in cardiovascular physiology and disease [PDF]

Open Biology, 2020
The a disintegrin-like and metalloproteinase with thrombospondin motif (ADAMTS) family comprises 19 proteases that regulate the structure and function of extracellular proteins in the extracellular matrix and blood.
Salvatore Santamaria, Rens de Groot
doaj   +1 more source