Results 121 to 130 of about 20,502 (253)

ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion injury [PDF]

, 2018
Highly adhesive glycoprotein von Willebrand factor (VWF) multimer induces platelet aggregation and leukocyte tethering or extravasation on the injured vascular wall, contributing to microvascular plugging and inflammation in brain ischemia-reperfusion. A
Akitake, Yoshiharu, Banno, Fumiaki, Fujioka, Masayuki, Fujiwara, Michihiro, Hayakawa, Kazuhide, Irie, Keiichi, Iwasaki, Katsunori, Kokame, Koichi, Mishima, Kenichi, Miyata, Toshiyuki, Muroi, Carl, Nakano, Takafumi, Nishio, Kenji, Okuchi, Kazuo, Sakamoto, Yuya, Siesjö, Bo, Yonekawa, Yasuhiro   +16 more
core  

Continuity of care in immune thrombotic thrombocytopenic purpura (iTTP): A visual roadmap for survivorship beyond acute management

Transfusion, EarlyView.
Jesse Qiao, Minh‐Ha Tran, Jennifer Jones, Sierra Simmons   +3 more
wiley   +1 more source

Lipoprotein(a), ABO Blood Types and Clinical Outcomes: Novel Findings and Clinical Implications in Patients With Chronic Coronary Syndrome

MedComm, Volume 6, Issue 12, December 2025.
The present study firstly revealed that the predictive value of Lp(a) for worse outcomes in chronic coronary syndrome patients with A or B blood group was stronger than that in the O group, suggesting that ABO blood group measurement may be clinically helpful for decision‐making in Lp(a) intervention. ABSTRACT This study aimed to investigate the effect
Hui‐Hui Liu, Chen‐Xi Song, Sha Li, Yan Zhang, Dong Yin, Wei‐Hua Song, Yuan‐Lin Guo, Cheng‐Gang Zhu, Na‐Qiong Wu, Rui‐Xia Xu, Qian Dong, Jie Qian, Yu‐Hui Zhang, Ke‐Fei Dou, Jian‐Jun Li   +14 more
wiley   +1 more source

Determination of ADAMTS13 and Its Clinical Significance for ADAMTS13 Supplementation Therapy to Improve the Survival of Patients with Decompensated Liver Cirrhosis

International Journal of Hepatology, 2011
The liver plays a central role in hemostasis by synthesizing clotting factors, coagulation inhibitors, and fibrinolytic proteins. Liver cirrhosis (LC), therefore, impacts on both primary and secondary hemostatic mechanisms.
Masahito Uemura, Yoshihiro Fujimura, Saiho Ko, Masanori Matsumoto, Yoshiyuki Nakajima, Hiroshi Fukui   +5 more
doaj   +1 more source

Síndrome Hemolítico Urémico Atípico en Cuidados Intensivos: Caso Clínico de un Adulto [PDF]

, 2016
info:eu-repo/semantics ...
Agudo, I, Azevedo, L, Bento, L, Cavaco, R, Germano, N, Souto-Moura, T   +5 more
core   +1 more source

Cuproptosis‐Related Ferroptosis Gene Signature: A Prognostic Tool for Colon Cancer Patients

Cancer Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background Ferroptosis and cuprotosis, two distinct mechanisms of programmed cell death, play key roles in colon cancer development. This study aimed to construct a prognostic model for predicting colon adenocarcinoma (COAD) prognosis based on the differential expression of cuproptosis‐related ferroptosis genes (CFRGs).
Yanlin Tan, Jinxiu Zhang, Ruoxi Cheng, Wenfang Yang, Xiaoping Pan, Kaoyan Feng, Mengbin Qin, Jie'an Huang   +7 more
wiley   +1 more source

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice

TH Open, 2017
Background Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity.
Naamah L. Zitomersky, Melanie Demers, Kimberly Martinod, Maureen Gallant, Stephen M. Cifuni, Amlan Biswas, Scott Snapper, Denisa D. Wagner   +7 more
doaj   +1 more source

Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper

Allergy, Volume 80, Issue 11, Page 2973-2987, November 2025.
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini, Alla Nakonechna, Annick Barbaud, Sevim Bavbek, Gianfranco Calogiuri, Inmaculada Doña, Violeta Kvedariene, Jose Julio Laguna Martinez, Serena Liberati, Mauro Pagani, Antonino Romano   +10 more
wiley   +1 more source

The effect of single nucleotide polymorphisms and mutations on congenital thrombotic thrombocytopenic purpura phenotype [PDF]

, 2017
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disease with a reported incidence of 6 cases per million per year in the UK. It is characterised by episodes of microangiopathic haemolytic anaemia and thrombocytopenia, with the ...
Tate, H., Tate, H.
core  

Thrombocytopeniak. [PDF]

, 2014
Thrombocytopenia means low platelet count. This is the most frequent cause of bleeding abnormalities. Petechias, purpuras, mucosal bleeding are typical clinical findings.
Domján, Gyula, Gadó, Klára
core   +1 more source