Generation of Inhibitory Autoantibodies to ADAMTS13 in Coronavirus Disease 2019 [PDF]
, 2021 Adrian Doevelaar +14 more
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ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology.
PLoS Biology, 2019 Blood-brain barrier (BBB) defects and cerebrovascular dysfunction contribute to amyloid-β (Aβ) brain accumulation and drive Alzheimer disease (AD) pathology.
Yongliang Cao +20 more
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Thirty five novel nsSNPs may effect on ADAMTS13 protein leading to Thrombotic thrombocytopenic purpura (TTP) using bioinformatics approach [PDF]
, 2019 Tebyan A. Abdelhameed +12 more
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ADAMTS13 reduces vascular inflammation and the development of early atherosclerosis in mice [PDF]
, 2011 Chintan Gandhi +3 more
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Clinical Dilemma in the Treatment of a Patient with Microangiopathic Haemolytic Anaemia, Thrombocytopaenia and Severe Hypertension [PDF]
, 2010 While haemolytic uraemic syndrome in children is predominantly associated with Shiga toxin -producing Escherichia coli (typically 0157:H7), some cases occur without associated diarrhoea, or as the manifestation of an underlying disorder other than ...
Castro, I, Gomes, D, Viegas, V
core
Regulation of ADAMTS13 by proteolitic enzymes
, 2007 Imperial Users ...
Lam, Jonathan Kai Yan +1 more
core
Deficiency of ADAMTS13 and thrombotic thrombocytopenic purpura [PDF]
, 2002 Han‐Mou Tsai
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Anti-ADAMTS13 Autoantibodies in Immune-Mediated Thrombotic Thrombocytopenic Purpura
AntibodiesAutoantibodies to ADAMTS13 are at the center of pathology of the immune-mediated thrombotic thrombocytopenic purpura. These autoantibodies can be either inhibitory (enzymatic function) or non-inhibitory, resulting in protein depletion.
Michael R. Snyder, Robert W. Maitta
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