A púrpura trombocitopênica trombótica (PTT) instala-se de modo abrupto e é caracterizada pela oclusão difusa de arteríolas e capilares da microcirculação, levando à isquemia de tecidos.
Leandro C. Tonaco+4 more
doaj
Accurate and efficient protein embedding using multi-teacher distillation learning [PDF]
Motivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction prediction, and protein structure prediction.
arxiv
Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]
,+4 more
core +1 more source
Protein Design with Dynamic Protein Vocabulary [PDF]
Protein design is a fundamental challenge in biotechnology, aiming to design novel sequences with specific functions within the vast space of possible proteins. Recent advances in deep generative models have enabled function-based protein design from textual descriptions, yet struggle with structural plausibility.
arxiv
The role of complement in Streptococcus pneumoniae-associated haemolytic uraemic syndrome [PDF]
Background. Atypical forms of haemolytic uraemic syndrome (aHUS) include HUS caused by defects in the regulation of alternative complement pathway and HUS linked to neuraminidase- producing pathogens, such as Streptococcus pneumoniae. Increasing data
Szilágyi, Ágnes
core
Clinical Dilemma in the Treatment of a Patient with Microangiopathic Haemolytic Anaemia, Thrombocytopaenia and Severe Hypertension [PDF]
While haemolytic uraemic syndrome in children is predominantly associated with Shiga toxin -producing Escherichia coli (typically 0157:H7), some cases occur without associated diarrhoea, or as the manifestation of an underlying disorder other than ...
Castro, I, Gomes, D, Viegas, V
core
Immune status assessment based on plasma proteomics with meta graph convolutional networks
Plasma proteins, especially immune-related proteins, are vital for assessing immune health and predicting disease risks. Despite their significance, the link between these proteins and systemic immune function remains unclear.
Min Zhang+8 more
doaj +1 more source
Development of a protease-resistant ADAMTS13 to improve stability against proteolytic degradation. [PDF]
DeYoung V+6 more
europepmc +1 more source
Advances in Research on the Release of von Willebrand Factor from Endothelial Cells through the Membrane Attack Complex C5b-9 in Sepsis. [PDF]
Liu Y+9 more
europepmc +1 more source
Complement activation in thrombotic thrombocytopenic purpura [PDF]
Alvarez-Larran+28 more
core +1 more source