Results 171 to 180 of about 3,354,179 (197)

Assessment of clinical characteristics, treatment responses, relapses, and survival in patients with thrombotic thrombocytopenic purpura undergoing therapeutic plasma exchange: A single-center experience. [PDF]

Pak J Med Sci
Dogan A, Ipek R.
europepmc   +1 more source

Hereditary Thrombotic Thrombocytopenic Purpura Associated With Recurrent Strokes and Prominent Nervous System Involvement in a Young Chinese Female. [PDF]

Clin Case Rep
Liu W, Wu J, Ming X, Zhang Q, Zhou D, Zheng R, Zhou M, Shang Z, Chen L, Zhu X, Xiao Y.   +10 more
europepmc   +1 more source

Clusterin maintains hemostatic equilibrium by stabilizing VWF multimers in plasma.

Blood
Qiao Z, Cao Y, Su J, Lu S, Wei G, Jin S, Ding Q, Sun Y, Huo Y, Dong M, Luo J, Li P.   +11 more
europepmc   +1 more source

The novel ADAMTS13-p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice

Journal of Thrombosis and Haemostasis, 2015
Summary: Background: Congenital thrombotic thrombocytopenic purpura (TTP) is characterized by mutations in the ADAMTS13 gene, which either impair protein secretion or influence ADAMTS13 (A Disintegrin-like And Metalloprotease domain with ThromboSpondin ...
Karen Vanhoorelbeke, Hans Deckmyn, S F de Meyer   +2 more
exaly   +2 more sources

ADAMTS13 in the New Era of TTP

International Journal of Molecular Sciences
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening, often immune-mediated disease that affects 2–13 persons per million per year.
Anna Papakonstantinou, Eleni Gavriilaki, Panagiotis Kalmoukos   +2 more
exaly   +2 more sources

Biologically active ADAMTS13 is expressed in renal tubular epithelial cells [PDF]

Pediatric Nephrology, 2010
ADAMTS13 mRNA, which encodes the von Willebrand factor-cleaving protease, has been detected in a variety of tissues, including the kidney. The aim of our study was to characterize tubular expression and bioactivity of ADAMTS13. ADAMTS13 mRNA was detected
Diana Karpman, Zivile Bekassy, Ramesh Tati   +2 more
exaly   +2 more sources

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An interactive database containing all known variants in ADAMTS13 yields new insight into the genetic variation and protein changes underlying congenital TTP

Blood
Abstract Introduction A disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13 (ADAMTS13) is encoded by a 45kb gene on chromosome 9q34.2. Deficiency leads to Thrombotic Thrombocytopenic Purpura (TTP), which exists as immune TTP (iTTP), or congenital TTP (cTTP), an ...
Matthew Carter, Imogen Buckle, Stephen Perkins, Marie Scully   +3 more
openaire   +1 more source

Factor VIII/protein C and not ADAMTS13/VWF:Ag ratio is a prognostic risk factor for patients with cirrhosis and low MELD score

Journal of Hepatology, 2020
N. Bitto, G. Tosetti, A. Tripodi, I. Mancini, L. Baronciani, C. Valsecchi, P. Lampertico, F. Peyvandi, M. Primignani, V. La Mura   +9 more
openaire   +1 more source

ADAMTS13 protein cell culture supernatant

2022
GRILLBERGER LEOPOLD, SPENGER ALEXANDRA, HASSLACHER MEINHARD, GRILLBERGER RANA, REITER MANFRED   +4 more
openaire   +1 more source

ADAMTS13 PROTEIN VARIANTS AND USES THEREOF

2021
VOORBERG JOHANNES JACOBUS, GOMES GRAÇA NUNO ALEXANDRE, ERÇIG BOGAÇ   +2 more
openaire   +2 more sources