Results 181 to 190 of about 8,844 (195)

[Effect of Recombinant Protein in the Spacer Domain on ADAMTS13 Activity].

Zhongguo shi yan xue ye xue za zhi, 2019
To obtain the recombinant protein of spacer domain in von Willebrand factor cleaving protease (ADAMTS13), and further study its biological function in ADAMTS13.The prokaryotic expression vector was constructed by using the template of plasmid with full-length ADAMTS13, and then transfected into E coli., following the induction of IPTG with the low ...
Zhen-Ni, Ma, Jing, Ling, Jie, Yin, Fei, Shen, Jian, Su, Li-Qian, Xie, Chang-Geng, Ruan   +6 more
openaire   +1 more source

Arginine Methylation on ADAMTS13 By Protein Arginine Methyltransferase 1 (PRMT1) Affects ADAMTS13 Secretion and Proteolytic Activity

Blood, 2022
Szumam Liu, Xinyang Zhao, X. Long Zheng
openaire   +1 more source

An interactive database containing all known variants in ADAMTS13 yields new insight into the genetic variation and protein changes underlying congenital TTP

Blood
Abstract Introduction A disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13 (ADAMTS13) is encoded by a 45kb gene on chromosome 9q34.2. Deficiency leads to Thrombotic Thrombocytopenic Purpura (TTP), which exists as immune TTP (iTTP), or congenital TTP (cTTP), an ...
Matthew Carter, Imogen Buckle, Stephen Perkins, Marie Scully   +3 more
openaire   +1 more source

Factor VIII/protein C and not ADAMTS13/VWF:Ag ratio is a prognostic risk factor for patients with cirrhosis and low MELD score

Journal of Hepatology, 2020
N. Bitto, G. Tosetti, A. Tripodi, I. Mancini, L. Baronciani, C. Valsecchi, P. Lampertico, F. Peyvandi, M. Primignani, V. La Mura   +9 more
openaire   +1 more source

ADAMTS13 activity, high VWF and FVIII levels in the pathogenesis of deep vein thrombosis

Thrombosis Research, 2021
Maria Teresa Pagliari, Andrea Cairo, Ilaria Mancini   +2 more
exaly  

Von Willebrand factor and ADAMTS13 impact on the outcome of Staphylococcus aureus sepsis

Journal of Thrombosis and Haemostasis, 2020
Sévérien Meyers, Laurens Liesenborghs, Christophe Vandenbriele   +2 more
exaly  

The novel ADAMTS13‐p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice

Journal of Thrombosis and Haemostasis, 2015
Hans Deckmyn, H Rottensteiner, Karen Vanhoorelbeke   +2 more
exaly  

Expression of ADAMTS13 in Normal and Abnormal Placentae and Its Potential Role in Angiogenesis and Placenta Development

Arteriosclerosis, Thrombosis, and Vascular Biology, 2017
Lei Fan, Xue Zeng, X Long Zheng
exaly  

Measurement and prevalence of circulating ADAMTS13‐specific immune complexes in autoimmune thrombotic thrombocytopenic purpura

Journal of Thrombosis and Haemostasis, 2014
Silvia Pontiggia, Ilaria Mancini, A Cannavo   +2 more
exaly  

Podocytes express ADAMTS13 in normal renal cortex and in patients with thrombotic thrombocytopenic purpura

British Journal of Haematology, 2007
Reinhard Schneppenheim, Moin A Saleem, Peter W Mathieson   +2 more
exaly