Results 171 to 180 of about 8,376 (205)

Recurrent Multi-territorial Ischemic Stroke As the Initial Presentation of Thrombotic Thrombocytopenic Purpura. [PDF]

Cureus
Reichman N, Biso GMN, Masoud H.
europepmc   +1 more source

The composition of single-donor apheresis platelet concentrates is influenced by the age of the donor. [PDF]

Sci Rep
Duchez AC, Arthaud CA, Eyraud MA, Prier A, Heestermans M, Hamzeh-Cognasse H, Cognasse F.   +6 more
europepmc   +1 more source

PLASMIC score to aid diagnosis of aHUS: an analysis of C5 inhibitor clinical trials and the PINC AI™ healthcare database. [PDF]

BMC Nephrol
Uriol-Rivera MG, Ernst FR, Booth JN, Comas À, Gasteyger C, Tomazos I, Lum C, Wang Y, Ávila AI.   +8 more
europepmc   +1 more source

Cytokine storm and microvascular fate: mechanistic insights into endothelial injury in thrombotic microangiopathies. [PDF]

Ann Med Surg (Lond)
Obeagu EI.
europepmc   +1 more source

Simvastatin Improve ADAMTS13 mRNA and Protein Expression in Podocytes.

Blood, 2012
Abstract Abstract 2246 Aim: ADAMTS13 is a specific VWF (von Willebrand factor) -cleaving protease, which severe deficiency is the main cause of thrombotic thrombocytopenic purpura. ADAMTS13 is mainly synthesized and released of the surface of hepatic stellate cells and endothelial cells,
Lei Shen, Guoyuan Lu, Ningzheng Dong, Zhenni Ma, Changgeng Ruan   +4 more
openalex   +3 more sources

Hematocrit and C‐reactive protein predict treatment response times in ADAMTS13‐deficient thrombotic microangiopathy

Journal of Clinical Apheresis, 2011
AbstractThrombotic microangiopathy (TMA) syndromes are a heterogeneous group of microvascular syndromes that are typically treated with plasma exchange and other adjunctive therapies. Important pathogenic factors, such as ADAMTS13 deficiency, define distinct subsets of TMA.
Noelle I. Samia, Kenneth D. Friedman, Jerome L. Gottschall, Thomas J. Raife   +3 more
openalex   +4 more sources

[Effect of Recombinant Protein in the Spacer Domain on ADAMTS13 Activity].

Zhongguo shi yan xue ye xue za zhi, 2019
To obtain the recombinant protein of spacer domain in von Willebrand factor cleaving protease (ADAMTS13), and further study its biological function in ADAMTS13.The prokaryotic expression vector was constructed by using the template of plasmid with full-length ADAMTS13, and then transfected into E coli., following the induction of IPTG with the low ...
Zhenni Ma, Jing Ling, Jie Yin, Fei Shen, Jian Su, Liqian Xie, Changgeng Ruan   +6 more
openalex   +4 more sources

Acute myocardial infarction as a systemic prothrombotic condition evidenced by increased von Willebrand factor protein over ADAMTS13 activity in coronary and systemic circulation

Heart and Vessels, 2008
The aim of the present study is to clarify the roles of circulating ADAMTS13 and von Willebrand factor (VWF) in the formation of coronary artery thrombi in acute myocardial infarction (AMI). Twenty-six AMI patients, 37 age-matched healthy controls, and 20 young controls were studied.
Manabu Horii, Shiro Uemura, Masahito Uemura, Masanori Matsumoto, Hiromichi Ishizashi, Keiichi Imagawa, Hajime Iwama, Yukiji Takeda, Hiroyuki Kawata, Tamio Nakajima, Yoshihiro Fujimura, Yoshihiko Saito   +11 more
openalex   +3 more sources