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Although a defect in ADAMTS13 activity is known to cause platelet thrombosis resulting in thrombotic thrombocytopenic purpura (TTP), recent evidence has revealed that low plasma ADAMTS13 concentrations may increase the risk of ischemic vascular diseases.
Kenichiro Enooku +10 more
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Abstract Abstract 487 Background. Acquired Thrombotic Thrombocytopenic Purpura (TTP) is the result of autoantibodies (Abs) neutralizing and/or accelerating clearance of ADAMTS13. Despite the first-line treatment with daily plasma exchange (PEX), acute TTP is still associated with a ...
Monica Schaller +6 more
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Twentieth Meeting of the European Neurological Society 19–23 June 2010 Berlin, Germany [PDF]
1MS Center, Department of Neurology, VU University Medical Center, Amsterdam, the Netherlands; 2Division of Clinical Neurology, University of Nottingham, UK; 3Merck Serono S.A. – Geneva, Switzerland*; 4Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, USA; 5Department of Neurology, University Hospital, Basel ...
Fumiaki Banno +16 more
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