Results 71 to 80 of about 5,385,083 (246)

Bacterial evolution and the Bak-Sneppen model [PDF]

, 2001
Recently, Lenski et al \cite{Elena,Lenski,Travisano} have carried out several experiments on bacterial evolution. Their findings support the theory of punctuated equilibrium in biological evolution. They have further quantified the relative contributions
Bose, Indrani, Chaudhuri, Indranath
core   +3 more sources

Oxidative proteome alterations during skeletal muscle ageing

Redox Biology, 2015
Sarcopenia corresponds to the degenerative loss of skeletal muscle mass, quality, and strength associated with ageing and leads to a progressive impairment of mobility and quality of life.
Sofia Lourenço dos Santos, Martin A. Baraibar, Staffan Lundberg, Orvar Eeg-Olofsson, Lars Larsson, Bertrand Friguet   +5 more
doaj   +1 more source

Predicting cortical bone adaptation to axial loading in the mouse tibia [PDF]

, 2015
The development of predictive mathematical models can contribute to a deeper understanding of the specific stages of bone mechanobiology and the process by which bone adapts to mechanical forces.
A. A. Pitsillides, A. F. Pereira, B. Javaheri, Cavanagh PR, Cowin SC, Frost HM, Phillips ATM, Robling AG, S. J. Shefelbine, Steck R   +9 more
core   +3 more sources

Generation of human induced pluripotent stem cell lines from five patients with Myofibrillar myopathy carrying different heterozygous mutations in the DES gene

Stem Cell Research
Myofibrillar myopathy (MFM) is a rare genetic disorder characterized by muscular dystrophy that is often associated with cardiac disease. This disease is caused by mutations in several genes, among them DES (encoding desmin) is the most frequently ...
Pierre Joanne, Yeranuhi Hovhannisyan, Alexandre Simon, Gaëlle Revet, Romain Diot, Gabriel Friob, Denisa Calin, Zhenlin Li, Anthony Béhin, Karim Wahbi, Gérard Tachdjian, Onnik Agbulut   +11 more
doaj   +1 more source

A genome‐wide investigation of the worldwide invader Sargassum muticum shows high success albeit (almost) no genetic diversity

Evolutionary Applications, 2020
Twenty years of genetic studies of marine invaders have shown that successful invaders are often characterized by native and introduced populations displaying similar levels of genetic diversity.
Sabrina Le Cam, Claire Daguin‐Thiébaut, Sarah Bouchemousse, Aschwin H. Engelen, Nova Mieszkowska, Frédérique Viard   +5 more
doaj   +1 more source

Cryptococcus neoformans Host Adaptation: Toward Biological Evidence of Dormancy

mBio, 2015
Cryptococcosis is an opportunistic infection due to the ubiquitous yeast Cryptococcus neoformans. This yeast interacts closely with innate immune cells, leading to various fates, including fungal persistence within cells, making possible the ...
A. Alanio, F. Vernel-Pauillac, Aude Sturny-Leclère, F. Dromer   +3 more
semanticscholar   +1 more source

Decreasing psychological distance to climate adaptation through serious gaming: Minions of Disruptions

Climate Services
A gap between knowledge and adaptive action remains and psychological distancing has been proposed to explain peoples’ inaction. This presents a challenge to climate change communication and particularly to the conventional ways of providing scientific ...
Minja Sillanpää, Julia Eichhorn, Sirkku Juhola   +2 more
doaj   +1 more source

Contribution of sustainable agricultural management practices to reduce the impacts of extreme weather events in Tropical America [PDF]

, 2014
One of the most accessible adaptation strategies for climate change and extreme weather events for smallholder farmers consists in the implementation of sustainable management practices.
Avelino, Jacques, Bautista Solis, Pavel, Chacon, Mario, Harvey, Celia A., Martinez, Ruth, Rapidel, Bruno, Trevejo, L., Vignola, Raffaele   +7 more
core  

Thioredoxin 2 protects mice against experimental myocardial infarction

Redox Experimental Medicine
Experimental Myocardial infarction (MI) using ligation procedure induces cardiac dysfunction, high level of ROS, inflammation, apoptosis, fibrosis and cardiomyocyte (CM) loss. AAV overexpressing human Trx-2, specifically in CM mitochondria improves mouse
Tania Medali, Dominique Couchie, Nathalie Mougenot, Maria Mihoc, Olaf Bergmann, Wouter Derks, Celio X Santos, Bertrand Friguet, Mustapha Rouis   +8 more
doaj   +1 more source

Increasing autophagy does not affect neurogenic muscle atrophy

European Journal of Translational Myology, 2018
Physiological autophagy plays a crucial role in the regulation of muscle mass and metabolism, while the excessive induction or the inhibition of the autophagic flux contributes to the progression of several diseases.
Eva Pigna, Krizia Sanna, Dario Coletti, Zhenlin Li, Ara Parlakian, Sergio Adamo, Viviana Moresi   +6 more
doaj   +1 more source