Results 101 to 110 of about 3,595,593 (336)

Developmental Adaptation to Stress: An Evolutionary Perspective.

Annual Review of Psychology, 2019
The assumption that early stress leads to dysregulation and impairment is widespread in developmental science and informs prevailing models (e.g., toxic stress).
B. Ellis, M. Del Giudice
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Mechanism of Salinity Tolerance in Plants: Physiological, Biochemical, and Molecular Characterization

International Journal of Genomics, 2014
Salinity is a major abiotic stress limiting growth and productivity of plants in many areas of the world due to increasing use of poor quality of water for irrigation and soil salinization.
Bhaskar Gupta, Bingru Huang
semanticscholar   +1 more source

Physiological adaptation of modern Ukrainian preschoolers

PULS UCZELNI, 2013
Introduction: High demands of modern social environment to the child’s individual development are connected with their health decline and wide variation of individual capabilities.
Olha Fedortsiv, Nataliia Luchyshyn, Zofia Pilarska, Karolina Chilicka-Jasionowska, Donata Kurpas   +4 more
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Physiological aspects on altitudinal hypoxia adaptation

Acta Biológica Colombiana, 2002
This review describes the physiological changes found in people adapted to inter-mediate altitude hypoxi.
Joel Alberto Rojas Jaramillo
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Hypoxia and metabolic adaptation of cancer cells

Oncogenesis, 2016
Low oxygen tension (hypoxia) is a pervasive physiological and pathophysiological stimulus that metazoan organisms have contended with since they evolved from their single-celled ancestors.
Katherine L. Eales, Kate E. R. Hollinshead, D. Tennant   +2 more
semanticscholar   +1 more source

Adaptation to Hysterectomy: Design and Psychometric Properties Assessment of Hysterectomy Adaptation Scale

Iranian Journal of Nursing and Midwifery Research
Background: Adaptation to complications of hysterectomy is one of the topics of concern for women and health care providers. There is no instrument for evaluating adaptation to hysterectomy.
Fatemeh Goudarzi, Raheleh Babazadeh, Abbas Ebadi, Talat Khadivzadeh   +3 more
doaj   +1 more source

Physiological and genomic evidence that selection on the transcription factor Epas1 has altered cardiovascular function in high-altitude deer mice.

PLoS Genetics, 2019
Evolutionary adaptation to extreme environments often requires coordinated changes in multiple intersecting physiological pathways, but how such multi-trait adaptation occurs remains unresolved.
Rena M Schweizer, Jonathan P Velotta, Catherine M Ivy, Matthew R Jones, Sarah M Muir, Gideon S Bradburd, Jay F Storz, Graham R Scott, Zachary A Cheviron   +8 more
doaj   +1 more source