Results 121 to 130 of about 2,568,811 (261)

PHYSIOLOGICAL AND SOCIO-PEDAGOGICAL PROBLEMS OF ADAPTATION AND HEALTH

Вестник Кемеровского государственного университета, 2013
The materials presented summarize the theoretical and practical aspects of the research carried out by the scientific school «Physiological and socio-pedagogical problems of adaptation and health».
E. M. Kazin, N. A. Litvinova, A. I. Fedorov, N. G. Blinova, L. A. Varich, N. P. Nedospasova, N. T. Rylova, O. L. Tarasova   +7 more
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Myo-inositol oxygenase: A key player in the battle of Pacific white shrimp (Penaeus vannamei) against low-salinity stress

Aquaculture Reports
Salinity is an important physicochemical parameter in the aquatic environment that has a profound impact on the physiological processes of aquatic animals. Therefore, strong salinity adaptability is crucial for the survival of aquatic animals.
Shengwei Lin, Yiting Wu, Zhihao Zhang, Xinchen Wang, Fenglu Han, Chang Xu, Erchao Li   +6 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Physiological adaptation of plateau mammals to hypoxia and cold: From organ systems to host-microbiome collaborative symbiosis

陆军军医大学学报
Animals primarily adapt to environmental changes through morphological, behavioral and physiological adjustments. Environmental factors, such as hypoxia, cold, and seasonal resource scarcity, pose significant challenges to animal survival. How to live in
WANG Dehua, GUO Na
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Adaptation in multisensory neurons

, 2008
The most studied region in the mammalian brain for multisensory integration is the deep superior colliculus (DSC). Neurophysiological experiments have revealed many response properties of DSC neurons, such as cross-modal enhancement (CME) and sub ...
Kuang, Xutao
core   +1 more source

Myocardial Fibrosis in Athletes: Risk Marker or Physiological Adaptation?

Biomedicines
Endurance exercise is widely recognized for its cardiovascular benefits, including improved longevity and metabolic health. However, excessive endurance training may lead to adverse cardiac adaptations, such as myocardial fibrosis, detected via late ...
Vasiliki Katsi, Epameinondas Triantafyllou, Christos Fragoulis, Christos Vazaios, Spyridon Maragkoudakis, Alexandros Kasiakogias, Charalampos Vlachopoulos, Konstantinos P. Tsioufis   +7 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Network governance and climate change adaptation: collaborative responses to the Queensland floods [PDF]

, 2013
 This research examines ways to build adaptive capacity to climate change, through a case study of organisations that participated in the response to Queensland’s major flood disaster in Queensland in 2010/11.
Kym Patison, Julie Mann, Susan Kinnear
core