Results 101 to 110 of about 358,354 (313)
What do we know about UK household adaptation to climate change? A systematic review [PDF]
, 2014 The UK Government’s first National Adaptation Programme seeks to create a ‘climate-ready society’ capable of making well-informed and far-sighted decisions to address risks and opportunities posed by a changing climate, where individual households are ...
Porter, J.J. +10 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
, 2019 While adaptations to local environments are well recognized, their actual influence on the dynamics of organisms (e.g., demography of mortality, growth, and reproduction) at a population level are less studied.
Peter Biro (13088787) +1 more
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Estrogen deficiency alters skeletal and metabolic responses to obesity and weight loss strategies
Bone Reports, 2020 Maude Gerbaix +7 more
doaj +1 more source
Membrane lipid unsaturation as physiological adaptation to animal longevity
Frontiers in Physiology, 2013 The appearance of oxygen in the terrestrial atmosphere represented an important selective pressure for ancestral living organisms and contributed toward setting up the pace of evolutionary changes in structural and functional systems.
Alba eNaudí +5 more
doaj +1 more source
Affective Videogames and Modes of Affective Gaming: Assist Me, Challenge Me, Emote Me [PDF]
, 2005 In this paper we describe the fundamentals of affective gaming from a physiological point of view, covering some of the origins of the genre, how affective videogames operate and current conceptual and technological capabilities.
Allanson, Jen, Dix, Alan, Gilleade, Kiel
core
Coupling Interaction and Physiological Metrics for Interaction Adaptation
, 2011 Part 1: Long and Short PapersInternational audienceWe present an adaptation system whose goal is to provide users with interaction experiences tailored to their current physiological status and performance.
Carriço, Luís +3 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Livestock robustness: physiological and behavioural levers of adaptation
, 2023 International audienceIn Mediterranean and Tropical livestock production systems, animals are faced with sometimes drastic variations in the availability of food resources, for example duringmore or less predictable and extended droughts, leading to ...
González García, Eliel +4 more
core