Results 81 to 90 of about 3,595,593 (336)

A physiological adaptation to undernutrition

open access: yesAnnals of Human Biology, 1994
A total of 432 children under the age of 10 years were measured for height and weight, and the morbidity and mortality indices were studied in six counties of the maize region of the state of Yucatán, Mexico. Undernutrition, because of its relationship to morbidity and mortality, was considered an important selection factor operating between the ages ...
G, Balam, F, Gurri
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Nutrition and Metabolic Adaptations in Physiological and Complicated Pregnancy: Focus on Obesity and Gestational Diabetes

open access: yesFrontiers in Endocrinology, 2020
Pregnancy offers a window of opportunity to program the future health of both mothers and offspring. During gestation, women experience a series of physical and metabolic modifications and adaptations, which aim to protect the fetus development and are ...
S. Parrettini, A. Caroli, E. Torlone
semanticscholar   +1 more source

A reinforcement learning theory for homeostatic regulation [PDF]

open access: yes, 2011
Reinforcement learning models address animal’s behavioral adaptation to its changing “external” environment, and are based on the assumption that Pavlovian, habitual and goal-directed responses seek to maximize reward acquisition.
Gutkin, B. S., Keramati, M.
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Ecology of Water Relations in Plants [PDF]

open access: yes, 2007
Water is an important resource for plant growth. Availability of water in the soil determines the niche, distribution and competitive interaction of plants in the ...
Archibold   +16 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Multiparameter vision testing apparatus [PDF]

open access: yes, 1975
Compact vision testing apparatus is described for testing a large number of physiological characteristics of the eyes and visual system of a human subject.
Homkes, R. J.   +3 more
core   +1 more source

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