Results 91 to 100 of about 1,276,486 (299)
Water loss in tree weta (Hemideina): adaptation to the montane environment and a test of the melanisation–desiccation resistance hypothesis [PDF]
, 2015 Keith King, Brent J. Sinclair
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
The safety of childhood as a fundamental issue of developing preschool education
Культурно-историческая психологияContext and relevance. At the beginning of the 21st century, preschool childhood is increasingly exposed to global civilizational influences, threatening its transformation into the initial stage of organized education and upbringing of a ...
Yu.I. Rodin, O.G. Ghugainova
doaj +1 more source
ColorMapGAN: Unsupervised Domain Adaptation for Semantic Segmentation\n Using Color Mapping Generative Adversarial Networks [PDF]
, 2019 Onur Taşar +3 more
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Reconstruction of long-term hourly sea level data for Prince Edward Island, Canada
Scientific DataRegional sea level rise has been regarded a key factor in understanding of climate change impact to coastal communities. As a vulnerable island to sea level rise and storm surges, the province of Prince Edward Island (PEI) in Canada lacks sufficient long-
Tianze Pang +3 more
doaj +1 more source
Measuring and Detecting Molecular Adaptation in Codon Usage Against Nonsense Errors During Protein Translation [PDF]
, 2009 Michael A. Gilchrist +2 more
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source