Results 81 to 90 of about 2,348,191 (254)
Frontiers in Immunology, 2016 Rasmussen encephalitis (RE) is a rare pediatric neuroinflammatory disease characterized by intractable seizures and unilateral brain atrophy. T cell infiltrates in affected brain tissue, and the presence of circulating autoantibodies in some RE patients ...
Sugandha Dandekar +5 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Collaborative tagging approaches for ontological metadata in adaptive e-learning systems
, 2006 One of the main approaches for creating metadata for learn- ing resources in adaptive e-learning systems has been through the use of semantic web ontologies.
() +3 more
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Learning algorithms for adaptive digital filtering [PDF]
, 1993 In this thesis, we consider the problem of parameter optimisation in adaptive digital filtering. Adaptive digital filtering can be accomplished using both Finite Impulse Response (FIR) filters and Infinite Impulse Response Filters (IIR) filters. Adaptive
Nambiar, Raghu
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Yeungnam University, Regional Adaptive Technology Center
, 1976 Text in ...
Yeungnam University, Regional Adaptive Technology Center
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Co-Phase Error Detection for Segmented Mirrors Based on Far-Field Information and Transfer Learning
PhotonicsThe resolution of a telescope is closely related to its aperture size; however, the aperture of a single primary mirror telescope cannot be indefinitely enlarged due to design and manufacturing constraints.
Kunkun Cheng +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source