Results 71 to 80 of about 3,810,680 (297)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Free-space optical communication is an effective alternative solution to address the “last mile” bottleneck in fiber-optic communication systems.
Ziting Pan +6 more
doaj +1 more source
Adapting Quality Assurance to Adaptive Systems: The Scenario Coevolution Paradigm
From formal and practical analysis, we identify new challenges that self-adaptive systems pose to the process of quality assurance. When tackling these, the effort spent on various tasks in the process of software engineering is naturally re-distributed.
C Bernon +16 more
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
RS-FeatFuseNet: An Integrated Remote Sensing Object Detection Model with Enhanced Feature Extraction
With the advancement of satellite and sensor technologies, remote sensing images are playing crucial roles in both civilian and military domains. This paper addresses challenges such as complex backgrounds and scale variations in remote sensing images by
Yijuan Qiu +5 more
doaj +1 more source
Fast Restoration of Aberration-Degraded Extended Object Based on Local Region Abstraction
The compensating capability of wavefront sensorless adaptive optics (WFSless AO) system for extended object images degraded by aberration is severely limited to correction speed due to largely sized images and low frame rate of camera.
Lianghua Wen +8 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Improving the detection of small objects in remote sensing is essential for its extensive use in various applications. The diminutive size of these objects, coupled with the complex backgrounds in remote sensing images, complicates the detection process.
Xiangyue Zheng +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

