Results 31 to 40 of about 109,797 (269)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Belief Revision for Adaptive Information Filtering Agents
, 2001 Agent-based information filtering alleviates the problem of information overload on the Internet by proactively scanning through the incoming stream of information on behalf of the users.
Bruza, Peter D. +4 more
core +1 more source
Adaptively Biasing the Weights of Adaptive Filters [PDF]
IEEE Transactions on Signal Processing, 2010 It is a well-known result of estimation theory that biased estimators can outperform unbiased ones in terms of expected quadratic error. In steady state, many adaptive filtering algorithms offer an unbiased estimation of both the reference signal and the unknown true parameter vector. In this correspondence, we propose a simple yet effective scheme for
Miguel Lázaro-Gredilla +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Observations on adaptive vector filters for noise reduction in color images
, 2004 In a series of papers, Plataniotis et al. proposed a number of filters for noise reduction in color images where the noise type is unknown. In this letter, those filters with a unified notation are summarized, and it is shown that they are essentially ...
Cree, Michael J.
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Adaptive digital signal processing Java teaching tool
, 2001 This publication presents a JAVA program for teaching the rudiments of adaptive digital signal processing (DSP) algorithms and techniques. Adaptive DSP is on of the most important areas of signal processsing, and provides the core algorithmic means to ...
Harteneck, M., Stewart, R.W.
core +1 more source
H ? filtering for stochastic singular fuzzy systems with time-varying delay [PDF]
, 2014 This paper considers the H? filtering problem for stochastic singular fuzzy systems with timevarying delay. We assume that the state and measurement are corrupted by stochastic uncertain exogenous disturbance and that the system dynamic is modeled ...
Cai, Min +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source