Results 41 to 50 of about 109,797 (269)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A Subband Adaptive Equalization Structure

, 1999
The potential presence of fractional delays, non-minimum phase parts, and a colouring of the channel output can require adaptive equalizers to adapt very long impulse responses.
Weiss, Stephan, S. Weiss, Weiss, S, Garcia-Alis, D, Garcia-Alis, Daniel, Stewart, R W, Stewart, Robert   +6 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Subband Adaptive Equaliser Tracking for Fractionally-Sampled Fading Broadband MIMO Channels [PDF]

, 2005
This paper demonstrates the performance of a subband adaptive multiple-input multiple-output (MIMO) equaliser tracking the inverse of a Doppler-filtered Rayleigh-fading broadband channel. The subband adaptive equaliser is shown to outperform the fullband
Weiss, Stephan, Weiss, S, Weiss, S., Bale, V, Bale, V., Bale, Viktor   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Subband decomposition techniques for adaptive channel equalisation

, 2005
In this contribution, the convergence behaviour of the adaptive linear equaliser based on subband decomposition technique is investigated. Two different subband-based linear equalisers are employed, with the aim of improving the equaliser's convergence ...
Weiss, Stephan, Arif, N.A.M., Alias, M.Y., Alias, Mohamad Yusoff, Arif, Nor Azhar Mohd, Arif, N. A. M., Weiss, S., Mohamad, Hafizal, Mohamad, H.   +8 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Feature Extracting in the Presence of Environmental Noise, using Subband Adaptive Filtering

, 2009
In this work, a new feature extracting method in noisy environments is proposed. The approach is based on subband decomposition of speech signals followed by adaptive filtering in the noisiest subbbands of speech.
Samad, Salina Abdul
core  

Distributed Asymptotic Minimization of Sequences of Convex Functions by a Broadcast Adaptive Subgradient Method [PDF]

, 2011
We propose a non-hierarchical decentralized algorithm for the asymptotic minimization of possibly time-varying convex functions. In our method, each agent in a network has a private, local (possibly time-varying) cost function, and the objective is to ...
Renato L. G. Cavalcante, Jennings, Nick, Isao Yamada, Cavalcante, Renato L. G., Rogers, A, Alex Rogers, Nicholas R. Jennings, Rogers, Alex, Yamada, I, Jennings, N, Yamada, Isao, Cavalcante, RLG   +11 more
core   +1 more source