Results 131 to 140 of about 5,026,401 (367)

Triiodothyronine suppresses humoral immunity but not T-cell-mediated immune response in incubating female eiders (Somateria mollissima)

, 2007
Immunity is believed to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction. Previous studies have shown that the acquired immunity of female common eiders (Somateria mollissima) is
Ahima, Apanius, Bourgeon, Bourgeon, Bourgeon, Criscuolo, Criscuolo, Deerenberg, Demas, Eraud, Erikstad, Faggioni, Fowles, Gabarrou, Gabrielsen, Gustafsson, Hanssen, Hanssen, Hanssen, Harvey, Korschgen, Lord, Lõhmus, Lõhmus, Martinez-Padilla, Martínez, Matarese, Matarese, McNabb, Merino, Moreno, Norris, Parham, Roitt, Råberg, Saino, Sechman, Sheldon, Smits, Sophie Bourgeon, Stearns, Thierry Raclot, Tomás, Verhulst, Williams, Williamson   +45 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Critical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1 [PDF]

, 2006
Fayyaz S. Sutterwala, Yasunori Ogura, Marian Szczepanik, María Lara‐Tejero, G. Scott Lichtenberger, Ethan Grant, John Bertin, Anthony J. Coyle, Jorge E. Galán, Philip W. Askenase, Richard A. Flavell   +10 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Repertoire-based mapping and time-tracking of T helper cell subsets in scRNA-Seq

Frontiers in Immunology
IntroductionThe functional programs of CD4+ T helper (Th) cell clones play a central role in shaping immune responses to different challenges. While advances in single-cell RNA sequencing (scRNA-Seq) have significantly improved our understanding of the ...
Daniil K. Lukyanov, Daniil K. Lukyanov, Valeriia V. Kriukova, Kristin Ladell, Irina A. Shagina, Irina A. Shagina, Dmitry B. Staroverov, Dmitry B. Staroverov, Bella E. Minasian, Anna S. Fedosova, Pavel Shelyakin, Oleg N. Suchalko, Alexander Y. Komkov, Konstantin A. Blagodatskikh, Kelly L. Miners, Olga V. Britanova, Olga V. Britanova, Olga V. Britanova, Andre Franke, David A. Price, David A. Price, Dmitry M. Chudakov, Dmitry M. Chudakov, Dmitry M. Chudakov, Dmitry M. Chudakov, Dmitry M. Chudakov   +25 more
doaj   +1 more source

The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function [PDF]

, 2016
Samuel E. Marsh, Edsel M. Abud, Anita Lakatos, Alborz Karimzadeh, Stephen T. Yeung, Hayk Davtyan, Gianna Fote, Lydia Lau, Jason G. Weinger, Thomas E. Lane, Matthew A. Inlay, Wayne W. Poon, Mathew Blurton‐Jones   +12 more
openalex   +1 more source

Deregulation of Adaptive T Cell Immunity in Multiple Myeloma: Insights Into Mechanisms and Therapeutic Opportunities [PDF]

, 2020
Noémie Leblay, Ranjan Maity, Fajer Hasan, Paola Neri   +3 more
openalex   +1 more source

Gut Microbiota Modulation on Intestinal Mucosal Adaptive Immunity

Journal of Immunological Research, 2019
The mammalian intestine harbors a remarkable number of microbes and their components and metabolites, which are fundamental for the instigation and development of the host immune system. The intestinal innate and adaptive immunity coordinate and interact
Li Wang, Limeng Zhu, S. Qin
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source