Results 151 to 160 of about 5,026,401 (367)

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

Nature reviews. Immunology, 2021
P. Roy, Marco Orecchioni, K. Ley
semanticscholar   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

The diversity, structure and function of heritable adaptive immunity sequences in the Aedes aegypti genome [PDF]

, 2017
Zachary J. Whitfield, Patrick Dolan, Mark Kunitomi, Michel Tassetto, Matthew G. Seetin, Steve D. Oh, Cheryl Heiner, Ellen E. Paxinos, Raul Andino   +8 more
openalex   +1 more source

Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity

Cell, 2020
C. Moderbacher, S. Ramirez, J. Dan, A. Grifoni, K. Hastie, D. Weiskopf, S. Bélanger, R. Abbott, Christina Kim, Jinyong Choi, Y. Kato, Eleanor G. Crotty, Cheryl Kim, Stephen A. Rawlings, J. Mateus, Long Ping Victor Tse, A. Frazier, R. Baric, Bjoern Peters, J. Greenbaum, E. Saphire, Davey M. Smith, A. Sette, S. Crotty   +23 more
semanticscholar   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes

ImmunoTargets and Therapy, 2017
Arata Itoh, William M Ridgway Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Type 1 diabetes (T1D) is characterized by specific destruction of pancreatic insulin-producing ...
Itoh A, Ridgway WM
doaj  

Differential Effects of Yin- and Yang-Chinese Tonifying Herbs on Innate and Adaptive Immunity

, 2023
Hoi Yan Leung, Kam Ming Ko
openalex   +2 more sources

Adaptive immunity induces mutualism between commensal eukaryotes

Nature, 2021
Kyla S. Ost, Teresa R. O’Meara, W. Stephens, Tyson R. Chiaro, Haoyang Zhou, Jourdan Penman, Rickesha S. Bell, J. Catanzaro, Deguang Song, Shakti Singh, Daniel H Call, Elizabeth Hwang-Wong, K. Hanson, J. Valentine, K. Christensen, Ryan M. O’Connell, B. Cormack, A. Ibrahim, Noah W. Palm, S. Noble, J. Round   +20 more
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Expression of MHC II genes

, 2005
Innate and adaptive immunity are connected via antigen processing and presentation (APP), which results in the presentation of antigenic peptides to T cells in the complex with the major histocompatibility (MHC) determinants.
Drozina, G., Jabrane-Ferrat, N., Kohoutek, J., Peterlin, B. M.   +3 more
core   +2 more sources