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The Adaptation Model of Immunity

Immunotherapy, 2013
Although 'self-nonself' and 'danger' theories have improved our understanding of the immune system, successful immunotherapy of cancer and many autoimmune diseases still remain far from reach. This indicates that our knowledge of how the immune system decides to respond effectively or ineffectively is limited.
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Adaptive immunity to mycobacteria

Current Opinion in Microbiology, 2004
Advances are now being made in terms of understanding both the initiation of the adaptive or acquired response to tuberculosis infection and its interface with elements of the innate response, as well as much later events in terms of the chronic disease state where reactivation can potentially occur.
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Adaptive Immunity in Immunothrombosis

Seminars in Thrombosis and Hemostasis
Abstract Thrombosis is a comorbidity associated with autoimmune, allergic, and infectious conditions; however, the mechanistic basis for this elevated risk is poorly understood. The simultaneous activation of the immune and coagulation systems to assist in response to injury and efficient pathogen clearance, termed immunothrombosis ...
David Noone   +2 more
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The Evolution of Adaptive Immunity

2012
The concept of adaptive immunity suggests de novo generation in each individual of extremely large repertoires of diversified receptors and selective expansion of receptors that match the antigen/pathogen. Accordingly, adaptive immune system is also called "anticipatory".
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Immune mechanisms: adaptive immunity

2016
The role of adaptive immunity (i.e. the involvement of B and T lymphocytes) in the pathogenesis of axial spondyloarthritis has been investigated in both human disease and relevant animal models. Studies of B cell responses have not generally implicated an autoantibody in the disease, but there are abnormalities of antibody responses, particularly ...
Maxime Breban, Hill Gaston
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The Adaptive Immunity

2016
Adaptive immunity develops during the lifetime of an organism as an adaptation to infection with certain pathogens, also referring to as the acquired immunity. Adaptive immune response is highly antigen specific, although it is relatively slow, it is highly efficient at antigen clearance, and therefore it is also termed as specific immunity.
Haoyu Sun, Cheng Sun, Zhigang Tian
openaire   +1 more source

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

Nature Reviews Immunology, 2021
Klaus Ley   +2 more
exaly  

The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity

Signal Transduction and Targeted Therapy, 2021
Sen Yang, Xiangyu Chen, Yaokai Chen
exaly  

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