Results 161 to 170 of about 9,268 (211)
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez +8 more
wiley +1 more source
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Journal of Allergy and Clinical Immunology, 2010
The innate immune system provides critical mechanisms for the rapid sensing and elimination of pathogens. Adaptive immunity has evolved to provide a broader and more finely tuned repertoire of recognition for both self- and nonself-antigens. Adaptive immunity involves a tightly regulated interplay between antigen-presenting cells and T and B ...
Francisco A, Bonilla, Hans C, Oettgen
+5 more sources
The innate immune system provides critical mechanisms for the rapid sensing and elimination of pathogens. Adaptive immunity has evolved to provide a broader and more finely tuned repertoire of recognition for both self- and nonself-antigens. Adaptive immunity involves a tightly regulated interplay between antigen-presenting cells and T and B ...
Francisco A, Bonilla, Hans C, Oettgen
+5 more sources
Adaptive immunity and atherosclerosis
Clinical Immunology, 2010Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most common causes of death globally. It has been evident for more than 20 years that adaptive immunity and T cells in particular regulate the magnitude of the atherogenic pro-inflammatory response.
Andersson J, Libby P, Hansson GK
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Adaptive innate immunity or innate adaptive immunity?
Clinical Science, 2019AbstractThe innate immunity is frequently accepted as a first line of relatively primitive defense interfering with the pathogen invasion until the mechanisms of ‘privileged’ adaptive immunity with the production of antibodies and activation of cytotoxic lymphocytes ‘steal the show’.
Jan Černý, Ilja Stříž
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Proceedings of International Conference on Neural Networks (ICNN'97), 2002
Immunized computational systems combine a priori knowledge with the adapting capabilities of immune systems to provide a powerful alternative to currently available techniques for intelligent control. In this paper, we present our perspective on various levels of intelligent control and relate them to similar functioning in human immune systems.
K. Krishnakumar, James C. Neidhoefer
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Immunized computational systems combine a priori knowledge with the adapting capabilities of immune systems to provide a powerful alternative to currently available techniques for intelligent control. In this paper, we present our perspective on various levels of intelligent control and relate them to similar functioning in human immune systems.
K. Krishnakumar, James C. Neidhoefer
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THE EVOLUTION OF ADAPTIVE IMMUNITY
Annual Review of Immunology, 2006Approximately 500 mya two types of recombinatorial adaptive immune systems appeared in vertebrates. Jawed vertebrates generate a diverse repertoire of B and T cell antigen receptors through the rearrangement of immunoglobulin V, D, and J gene fragments, whereas jawless fish assemble their variable lymphocyte receptors through recombinatorial usage of ...
Zeev, Pancer, Max D, Cooper
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Critical Reviews™ in Immunology, 2011
Adaptive immunity, involving distinctive antibody- and cell-mediated responses to specific antigens based on "memory" of previous exposure, is a hallmark of higher vertebrates. It has been argued that adaptive immunity arose rapidly, as articulated in the "big bang theory" surrounding its origins, which stresses the importance of coincident whole ...
Clifford, Liongue +2 more
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Adaptive immunity, involving distinctive antibody- and cell-mediated responses to specific antigens based on "memory" of previous exposure, is a hallmark of higher vertebrates. It has been argued that adaptive immunity arose rapidly, as articulated in the "big bang theory" surrounding its origins, which stresses the importance of coincident whole ...
Clifford, Liongue +2 more
openaire +2 more sources
Evolution of adaptive immunity
Biology Bulletin, 2009The current state of the problem of emergence and evolution of adaptive immunity in different taxonomic groups of animals is analyzed. Special attention is given to the emergence and phylogenetic development of the lymphocyte, the key component of immune response, as well as to the evolutionary development of T- and B-cell immune systems, adaptive ...
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Temperature and adaptive immunity
2018The adaptive immune response has evolved over hundreds of millions of years to have exquisitely specific and durable mechanisms to eliminate pathogenic threats wherever they may occur in the body. Temperature has long been known to influence the response to infections, injuries, and even cancer; however, the mechanistic basis of these effects has only ...
Michelle M, Appenheimer, Sharon S, Evans
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