Adaptive laboratory evolution of β-caryophyllene producing Saccharomyces cerevisiae [PDF]
Microbial Cell Factories, 2021 Background β-Caryophyllene is a plant terpenoid with therapeutic and biofuel properties. Production of terpenoids through microbial cells is a potentially sustainable alternative for production.
Avinash Godara, Katy C. Kao
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Adaptive laboratory evolution accelerated glutarate production by Corynebacterium glutamicum [PDF]
Microbial Cell Factories, 2021 Background The demand for biobased polymers is increasing steadily worldwide. Microbial hosts for production of their monomeric precursors such as glutarate are developed.
Carina Prell +5 more
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Adaptive Laboratory Evolution of Yeasts for Aroma Compound Production
Fermentation, 2022 Aroma compounds are important in the food and beverage industry, as they contribute to the quality of fermented products. Yeasts produce several aroma compounds during fermentation. In recent decades, production of many aroma compounds by yeasts obtained
Seyma Hande Tekarslan-Sahin
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Adaptive laboratory evolution of a genome-reduced Escherichia coli [PDF]
Nature Communications, 2019 Genome-reduced bacteria often show impaired growth under laboratory conditions. Here the authors use adaptive laboratory evolution to optimise growth performance and show transcriptome and translatome-wide remodeling of the organism.
Donghui Choe +8 more
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Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae [PDF]
Nature Communications, 2020 Methylotrophic metabolism enables growth on methanol, an alternative to sugar fermentation. Here the authors use adaptive laboratory evolution to uncover native methylotrophy capacity in Saccharomyces cerevisiae.
Monica I. Espinosa +8 more
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Biosensor-Assisted Adaptive Laboratory Evolution for Violacein Production [PDF]
International Journal of Molecular Sciences, 2021 Violacein is a naturally occurring purple pigment, widely used in cosmetics and has potent antibacterial and antiviral properties. Violacein can be produced from tryptophan, consequently sufficient tryptophan biosynthesis is the key to violacein production.
Da-ae Gwon +3 more
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Recent progress in adaptive laboratory evolution of industrial microorganisms. [PDF]
J Ind Microbiol Biotechnol, 2023 AbstractAdaptive laboratory evolution (ALE) is a technique for the selection of strains with better phenotypes by long-term culture under a specific selection pressure or growth environment. Because ALE does not require detailed knowledge of a variety of complex and interactive metabolic networks, and only needs to simulate natural environmental ...
Wang G +5 more
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Adaptive laboratory evolution – principles and applications for biotechnology [PDF]
Microbial Cell Factories, 2013 Adaptive laboratory evolution is a frequent method in biological studies to gain insights into the basic mechanisms of molecular evolution and adaptive changes that accumulate in microbial populations during long term selection under specified growth conditions.
Dragosits, Martin, Mattanovich, Diethard
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Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories [PDF]
Proceedings of the National Academy of Sciences, 2022 Human infections with methicillin-resistantStaphylococcus aureus(MRSA) are commonly treated with vancomycin, and strains with decreased susceptibility, designated as vancomycin-intermediateS. aureus(VISA), are associated with treatment failure. Here, we profiled the phenotypic, mutational, and transcriptional landscape of 10 VISA strains adapted by ...
Anaëlle Fait +6 more
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Ecological use of vertebrate surrogate species in ecosystem conservation
Global Ecology and Conservation, 2020 Surrogate species approaches are widely employed by conservation biologists to help address biodiversity conservation issues when distribution and abundance data for most species of conservation concern are not available or are limited due to ...
Chao Zhang +5 more
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