Adaptive Laboratory Evolution of Microorganisms: Methodology and Application for Bioproduction
Adaptive laboratory evolution (ALE) is a useful experimental methodology for fundamental scientific research and industrial applications to create microbial cell factories.
Takashi Hirasawa, Tomoya Maeda
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Atopic dermatitis (AD) is the most common heterogeneous skin disease. Currently, effective primary prevention approaches that hamper the occurrence of mild to moderate AD have not been reported.
Shengnan He +6 more
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Cloning and expression analysis of HXK1 gene from Jatropha curcas L.
HXK (Hexokinase) gene family and the role of JcHXK1 in Jatropha curcas L. were explored. Totally 4 HXK genes JcHXK1, JcHXK2, JcHXK3 and JcHKL1 were identified and complete ORF of JcHXK1 was cloned.
Hu Xin +8 more
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The role of calcium and predation on plate morph evolution in the three-spined stickleback (Gasterosteus aculeatus) [PDF]
While the genetic basis to plate morph evolution of the three-spined stickleback (Gasterosteus aculeatus) is well described, the environmental variables that select for different plate and spine morphs are incompletely understood.
Przybylski, Miroslaw +14 more
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Global warming is becoming the future climate trend and will have a significant impact on small mammals, and they will also adapt at the physiological levels in response to climate change, among which the adaptation of energetics is the key to their ...
Jiahong Feng +7 more
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An adjusted ELISpot-based immunoassay for evaluation of SARS-CoV-2-specific T-cell responses
Like antibody evaluation, using an effective antigen-specific T-cell immunity assessment method in coronavirus disease 2019 (COVID-19) patients, survivors and vaccinees is crucial for understanding the immune persistence, prognosis assessment, and ...
Hao Lin +7 more
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Adaptive laboratory evolution of Escherichia coli under acid stress
The ability of Escherichia coli to tolerate acid stress is important for its survival and colonization in the human digestive tract. Here, we performed adaptive laboratory evolution of the laboratory strain E.
Xu, Sibei +12 more
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Microbial Cell Factories / Adaptive laboratory evolution – principles and applications for biotechnology [PDF]
Adaptive laboratory evolution is a frequent method in biological studies to gain insights into the basic mechanisms of molecular evolution and adaptive changes that accumulate in microbial populations during long term selection under specified growth ...
Dragosits, Martin +3 more
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Application of Microalgal Stress Responses in Industrial Microalgal Production Systems
Adaptive laboratory evolution (ALE) has been widely utilized as a tool for developing new biological and phenotypic functions to explore strain improvement for microalgal production.
Jia Wang +9 more
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The evolutionary dynamics of adaptive virginity, sex-allocation and altruistic helping in haplodiploid animals [PDF]
In haplodiploids, females can produce sons from unfertilized eggs without mating. However, virgin reproduction is usually considered to be a result of a failure to mate, rather than an adaptation.
Mikael Puurtinen +5 more
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