Results 51 to 60 of about 6,281,815 (256)

High-altitude environments enhance the ability of Eothenomys miletus to regulate body mass during food limitation, with a focus on gut microorganisms and physiological markers

Frontiers in Microbiology
Animals’ digestion, energy metabolism, and immunity are significantly influenced by interactions between the gut microbiota and the intestinal environment of the host.
Tianxin Zhang, Tianxin Zhang, Ting Jia, Ting Jia, Wanlong Zhu, Wanlong Zhu, Wanlong Zhu, Lixian Fan, Lixian Fan   +8 more
doaj   +1 more source

Whole-genome sequencing analysis of two heat-evolved Escherichia coli strains

BMC Genomics, 2023
Background High temperatures cause a suite of problems for cells, including protein unfolding and aggregation; increased membrane fluidity; and changes in DNA supercoiling, RNA stability, transcription and translation.
Bailey E. McGuire, Francis E. Nano
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Rapidly evolving genes and stress adaptation of two desert poplars, Populus euphratica and P. pruinosa [PDF]

, 2013
Understanding which genes have evolved rapidly with the recent tree speciation in arid habitats can provide valuable insights into different adaptation mechanisms. We employed a comparative evolutionary analysis of expressed sequence tags (ESTs) from two
Penghui Xie (420345), Zhang, Jian, Jianquan Liu (200999), Zhang Jian, Meagher Thomas R., Meagher, Thomas R., Lascoux, Martin, Xie, Penghui, Liu, Jianquan, Thomas R Meagher, Xie Penghui, Lascoux Martin, Martin Lascoux, Jian Zhang (1682), Martin Lascoux (201001), Jianquan Liu, Liu Jianquan, Jian Zhang, Lascoux, Martin,, Thomas R. Meagher (420346), Meagher, Thomas Robert, Penghui Xie   +21 more
core   +1 more source

Large-scale geographic patterns and environmental and anthropogenic drivers of wetland plant diversity in the Qinghai-Tibet Plateau

BMC Ecology and Evolution
Background The geographic patterns of plant diversity in the Qinghai-Tibet Plateau (QTP) have been widely studied, but few studies have focused on wetland plants. This study quantified the geographic patterns of wetland plant diversity in the QTP through
Yigang Li, Fan Liu, Yadong Zhou, Xing Liu, Qingfeng Wang   +4 more
doaj   +1 more source

Continuous Adaptive Evolution of a Fast-Growing Corynebacterium glutamicum Strain Independent of Protocatechuate

Frontiers in Microbiology, 2019
Corynebacterium glutamicum is a commonly applied host for the industrial production of amino acids. While valued for its robustness, it is somewhat inferior to competing strains such as Escherichia coli because of the relatively low growth rate of 0.40 h−
Michaela Graf, Thorsten Haas, Felix Müller, Anina Buchmann, Julia Harm-Bekbenbetova, Andreas Freund, Alexander Nieß, Marcus Persicke, Jörn Kalinowski, Bastian Blombach, Bastian Blombach, Ralf Takors   +11 more
doaj   +1 more source

Rare peptide anchors of HLA class I alleles contribute to the COVID-19 disease severity and T cell memory

Biosafety and Health, 2023
Understanding how human leukocyte antigen (HLA) polymorphism affects both the susceptibility and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection will help to identify individuals at higher risk to better manage and ...
Xin Wang, Jie Zhang, Peipei Guo, Yuanyuan Guo, Xiaonan Yang, Maoshun Liu, Danni Zhang, Yaxin Guo, Jianbo Zhan, Kun Cai, Jikun Zhou, Shaobo Dong, Jun Liu   +12 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Long-Term Monitoring Reveals Changes in the Small Mammal Community Composition and Co-Occurrence Patterns in the Diannan Area of Yunnan, China

Biology
Long-term monitoring of small mammal communities provides critical insights into biodiversity conservation by detecting ecosystem degradation and quantifying anthropogenic impacts.
Jinyu Yang, Ting Jia, Wanlong Zhu, Xiaomi Yang   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source