Results 51 to 60 of about 110,599 (252)

Influences of environmental and chemical parameters on the spatial growth patterns of four riverine cyprinid fishes

Knowledge and Management of Aquatic Ecosystems, 2015
Understanding intraspecific variability in fish somatic growth rates is important as growth is a key life history trait that plays a fundamental role in many biological and ecological processes.
Liu C., Chen Y., Britton J.R.
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Insights from the high-altitude animal gut adaptation model: mechanisms of obesity regulation via microbiota-derived metabolite homeostasis and the gut-X axis

Frontiers in Microbiology
The unique environmental conditions at high altitudes drive the gut microbiota of resident animals to develop distinct structural and functional traits, thereby offering an ideal natural model for investigating the synergistic adaptation of hosts and ...
Lijuan Cao, Wanlong Zhu, Wanlong Zhu
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

High-altitude environments enhance the ability of Eothenomys miletus to regulate body mass during food limitation, with a focus on gut microorganisms and physiological markers

Frontiers in Microbiology
Animals’ digestion, energy metabolism, and immunity are significantly influenced by interactions between the gut microbiota and the intestinal environment of the host.
Tianxin Zhang, Tianxin Zhang, Ting Jia, Ting Jia, Wanlong Zhu, Wanlong Zhu, Wanlong Zhu, Lixian Fan, Lixian Fan   +8 more
doaj   +1 more source

Whole-genome sequencing analysis of two heat-evolved Escherichia coli strains

BMC Genomics, 2023
Background High temperatures cause a suite of problems for cells, including protein unfolding and aggregation; increased membrane fluidity; and changes in DNA supercoiling, RNA stability, transcription and translation.
Bailey E. McGuire, Francis E. Nano
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Large-scale geographic patterns and environmental and anthropogenic drivers of wetland plant diversity in the Qinghai-Tibet Plateau

BMC Ecology and Evolution
Background The geographic patterns of plant diversity in the Qinghai-Tibet Plateau (QTP) have been widely studied, but few studies have focused on wetland plants. This study quantified the geographic patterns of wetland plant diversity in the QTP through
Yigang Li, Fan Liu, Yadong Zhou, Xing Liu, Qingfeng Wang   +4 more
doaj   +1 more source

Continuous Adaptive Evolution of a Fast-Growing Corynebacterium glutamicum Strain Independent of Protocatechuate

Frontiers in Microbiology, 2019
Corynebacterium glutamicum is a commonly applied host for the industrial production of amino acids. While valued for its robustness, it is somewhat inferior to competing strains such as Escherichia coli because of the relatively low growth rate of 0.40 h−
Michaela Graf, Thorsten Haas, Felix Müller, Anina Buchmann, Julia Harm-Bekbenbetova, Andreas Freund, Alexander Nieß, Marcus Persicke, Jörn Kalinowski, Bastian Blombach, Bastian Blombach, Ralf Takors   +11 more
doaj   +1 more source

Rare peptide anchors of HLA class I alleles contribute to the COVID-19 disease severity and T cell memory

Biosafety and Health, 2023
Understanding how human leukocyte antigen (HLA) polymorphism affects both the susceptibility and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection will help to identify individuals at higher risk to better manage and ...
Xin Wang, Jie Zhang, Peipei Guo, Yuanyuan Guo, Xiaonan Yang, Maoshun Liu, Danni Zhang, Yaxin Guo, Jianbo Zhan, Kun Cai, Jikun Zhou, Shaobo Dong, Jun Liu   +12 more
doaj   +1 more source