Results 31 to 40 of about 84,822 (253)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Grey Fuzzy Sliding Mode Control with Grey Estimator for Brushless Doubly Fed Motor [PDF]

, 2010
In this paper, a grey fuzzy sliding mode controller (GFSMC) for brushless doubly fed motor (BDFM) adjustable speed system is presented. A grey model estimator and adaptive fuzzy control technology are incorporated into the sliding mode control (SMC) to ...
Guo, Y, Shao, Z, Zhan, Y, Zhu, J
core  

A novel robust adaptive control algorithm with finite-time online parameter estimation of a humanoid robot arm [PDF]

, 2014
A novel robust adaptive control algorithm is proposed and implemented in real-time on two degrees-of-freedom (DOF) of the humanoid Bristol-Elumotion-Robotic-Torso II (BERT II) arm in joint-space.
Herrmann, Guido, Khan, Said G, Mahyuddin, Muhammad Nasiruddin   +2 more
core   +2 more sources

Gain adaptation in sliding mode control of robotic manipulators

International Journal of Systems Science, 2000
In this paper, a novel scheme is proposed to adapt the gains of a sliding mode controller (SMC) so that the problems faced in its practical implementations as a motion controller are overcome. A Lyapunov function is selected for the design of the SMC and an MIT rule is used for gain adaptation.
Meliksah Ertugrul, Okyay Kaynak, Feza Kerestecioglu   +2 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Nonlinear robust controller design for thyristor controlled series compensation [PDF]

, 2009
Makalenin ilk sayfası mevcut.The problem of transient stability for a single machine infinite bus system with thyristor controlled series compensation (TCSC) is addressed in this paper.
Dimirovski, Georgi M., Sun, Li Ying, Zhao, Jun   +2 more
core  

Discrete Adaptive Second Order Sliding Mode Controller Design with Application to Automotive Control Systems with Model Uncertainties

, 2017
Sliding mode control (SMC) is a robust and computationally efficient solution for tracking control problems of highly nonlinear systems with a great deal of uncertainty.
Amini, Mohammad Reza, Hedrick, J. Karl, Pan, Selina, Shahbakhti, Mahdi   +3 more
core   +1 more source

Sliding mode adaptive state observation for time-delay uncertain nonlinear systems [PDF]

, 2008
In this paper a method to design robust adaptive sliding mode observers (ASMO) for a class of nonlinear time- delay systems with uncertainties, is proposed. The objective is to achieve insensitivity and robustness of the proposed sliding mode observer to
Raoufi, R., Zinober, A.S.I.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source