Results 31 to 40 of about 17,659 (264)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Parallel robot with fuzzy neural network sliding mode control

Advances in Mechanical Engineering, 2018
With the advancement in research on parallel robots, control theory is increasingly applied in the field of robotics. Owing to its robustness, sliding mode variable structure control is extensively used in parallel robots.
Jiangmin Xu, Qi Wang, Qing Lin
doaj   +1 more source

Advanced Adaptive Fault Diagnosis and Tolerant Control for Robot Manipulators

Energies, 2019
In this paper, an adaptive Takagi–Sugeno (T–S) fuzzy sliding mode extended autoregressive exogenous input (ARX)–Laguerre proportional integral (PI) observer is proposed.
Farzin Piltan, Cheol-Hong Kim, Jong-Myon Kim   +2 more
doaj   +1 more source

Variations in Finite-Time Multi-Surface Sliding Mode Control for Multirotor Unmanned Aerial Vehicle Payload Delivery with Pendulum Swinging Effects

Machines, 2023
Multi-surface sliding mode control addresses the limitations of traditional sliding mode control by employing multiple sliding surfaces to handle uncertainties, disturbances, and nonlinearities.
Clevon Peris, Michael Norton, Sui Yang Khoo   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Disturbance attenuation–based sliding mode control with disturbance observer for mismatched uncertain system

Advances in Mechanical Engineering, 2017
A disturbance attenuation–based sliding mode control approach with an extended disturbance observer is proposed for systems with mismatched uncertainties. A novel adaptive sliding surface consisting of the disturbance estimation is presented to eliminate
Jianguo Guo, Yuchao Liu, Cheng Cheng, Jun Zhou   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

PSO based neuro fuzzy sliding mode control for a robot manipulator

Journal of Electrical Systems and Information Technology, 2017
This paper presents the control strategy of two degrees of freedom (2DOF) rigid robot manipulator based on the coupling of artificial neuro fuzzy inference system (ANFIS) with sliding mode control (SMC).
M. Vijay, Debashisha Jena
doaj   +1 more source

Global robust super-twisting algorithm with adaptive switching gains for a hybrid robot

International Journal of Advanced Robotic Systems, 2020
To improve the robustness performance of dynamic sliding mode control to the time-varying uncertainties without the upper bound information in a hybrid robot system, a global robust super-twisting algorithm with adaptive switching gains is proposed.
Guoqin Gao, Songyun Zhang, Mengyang Ye
doaj   +1 more source

Design of RBF Adaptive Sliding Mode Controller for A Supercavitating Vehicle

IEEE Access, 2021
This paper proposes an adaptive sliding mode control strategy based on RBF (Radial Basis Function) neural network for the supercavitating vehicle system with model uncertainties and external disturbance.
Wang Jinghua, Liu Yang, Cao Guohua, Zhao Yongyong, Zhang Jiafeng   +4 more
doaj   +1 more source