Results 51 to 60 of about 17,659 (264)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Observer-Based Model-Free Adaptive Sliding Mode Predictive Control

open access: yesIEEE Access, 2023
This paper proposes a new observer-based model-free adaptive sliding mode predictive control method (MFASPC) for discrete-time nonlinear systems. This scheme first equates the discrete-time nonlinear system to a linear form using a data-driven compact ...
Bing Ren, Guangqing Bao
doaj   +1 more source

Application of MPC and sliding mode control to IFAC benchmark models [PDF]

open access: yes, 2008
The comparison of Model Predictive Control (MPC) and Sliding Mode Control (SMC) are presented in this paper. This paper investigates the performance of each controller as the navigation system for IFAC benchmark ship models (cargo vessel and oil tanker)
Anderson, D., McGookin, M., McGookin, E.
core  

Adaptive fuzzy sliding mode control for active front steering system

open access: yes, 2020
In order to alleviate the adverse effects of uncertainty in the active front steering (AFS) system , a new type of observer is designed in this paper that can simultaneously estimate the sideslip angle and disturbance, which provides the controller with ...
Liandi Fang   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Tensor Product Model Transformation Based Adaptive Integral-Sliding Mode Controller: Equivalent Control Method

open access: yesThe Scientific World Journal, 2013
This paper proposes new methodologies for the design of adaptive integral-sliding mode control. A tensor product model transformation based adaptive integral-sliding mode control law with respect to uncertainties and perturbations is studied, while upper
Guoliang Zhao, Kaibiao Sun, Hongxing Li
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Adaptive Trajectory Tracking Control for Rotorcraft Using Incremental Backstepping Sliding Mode Control Strategy

open access: yesInternational Journal of Aerospace Engineering, 2021
This paper investigates the adaptive incremental backstepping sliding mode control for the rotorcraft trajectory-tracking control problem to enhance the robustness to the matched uncertainty in the model.
Moon Gyeang Cho   +4 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Synchronization and Antisynchronization of Identical 4D Hyperchaotic Financial System with External Perturbation via Sliding Mode Control Technique

open access: yesComplexity, 2022
In this article, complete synchronization and antisynchronization in the identical financial chaotic system are presented. The proposed control strategies depend on first-order sliding mode and adaptive integral sliding mode for complete synchronization ...
Fazal ur Rehman   +5 more
doaj   +1 more source

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