Results 171 to 180 of about 4,471,539 (245)

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

Low Preoperative Free Triiodothyronine, Particularly in Females, Is Associated With Reduced Weight Loss and Diabetes Remission After Bariatric Surgery in Euthyroid Adults

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Aims With the rising prominence of GLP‐1 receptor agonists, identifying predictors of optimal bariatric surgery candidates has become increasingly important. We investigated cross‐sectional relationships between thyroid hormones and obesity‐related parameters, and evaluated the predictive value of baseline thyroid hormones for weight loss (WL)
Shaobo Li, Yinfang Tu, Hongwei Zhang, Yunfeng Xiao, Yuqian Bao, Jun Yin, Yujin Ma, Haoyong Yu, Fengjing Liu   +8 more
wiley   +1 more source

Short-term heat exposure affects thermogenesis and mitophagy in goat brown adipocytes

BMC Genomics
Background Brown adipose tissue (BAT) has a significant impact in newborn goats on maintaining body temperature through non-shivering thermogenesis in response to cold exposure. However, the roles of heat treatment on BAT thermogenesis are still limited.
Yulong Song, Die Li, Duo Su, Tingting Jiang, Longrui Li, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Jiaxue Cao, Li Li, Hongping Zhang, Linjie Wang   +11 more
doaj   +1 more source

Combination Pharmacotherapies for Obesity—Current Evidence and Future Directions

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Combination pharmacotherapy for obesity can enhance weight loss by targeting complementary neuroendocrine and metabolic pathways. Such benefits are largely additive but limited by tolerability, cost and access. This review outlines practical clinical archetypes and a research agenda for safer, more precise and durable combination strategies across ...
A. B. M. Kamrul‐Hasan, Arnav Kalra, Nitin Kapoor, Deep Dutta, Kunal Mahajan, Robin Maskey, Syed Abbas Raza   +6 more
wiley   +1 more source

MRP8‐Cre Transgenic Mice Are Resistant to Weight Gain and Diet‐Induced Obesity Independently of Neutrophils

European Journal of Immunology, Volume 56, Issue 9, September 2026.
The MRP8Cre mouse model is frequently used to investigate the biology of neutrophils. This study reports that MRP8Cre transgenic have a lower body weight and improved metabolic health, especially after high fat diet feeding, which correlates with decreased Serpine1/PAI‐1 expression in metabolic organs. Image created with BioRender.com. ABSTRACT Obesity
Stephan Forisch, Fatemeh Soltani, Laia Salvat Costa, Beatriz M. Cardoso, Yaiza Moreno Galiano, Cedric Duval, Robert A. S. Ariëns, Navdeep S. Chandel, Mari T. Kaartinen, Stefanie K. Wculek   +9 more
wiley   +1 more source

Absence of adaptive nonshivering thermogenesis in a marsupial, the fat-tailed dunnart (Sminthopsis crassicaudata)

, 2012
The presence of nonshivering thermogenesis in marsupials is controversially debated. Survival of small eutherian species in cold environments is crucially depen- dent on uncoupling protein 1 (UCP1)-mediated, adaptive nonshivering thermogenesis ...
Elias Polymeropoulos (14746963), Jastroch, M (15538856), Peter Frappell (14736940)   +2 more
core  

Kiwifruit Seed Polyphenols Ameliorate High‐Fat‐Induced Obese Mice via Inhibition of Inflammation and Regulation of Gut Microbiota Balance

Food Frontiers, Volume 7, Issue 5, September 2026.
Kiwifruit seed polyphenols (KSP) alleviate high‐fat diet‐induced obesity and metabolic dysfunction in mice by reducing body weight gain, adiposity, hepatic steatosis, and insulin resistance. KSP also suppresses inflammation, improves lipid metabolism, and reshapes gut microbiota composition, restoring short‐chain fatty acid production, thereby ...
Qingqing Liu, Jianxin Huang, Jinyue Xu, Qi Zhang, Ying Zhang, Haixia Yang, Wei Cao, Jianjun Deng   +7 more
wiley   +1 more source

Decadal Bowhead Whale Baleen Stable Isotope and Hormone Chronologies (1985–2010) Provide Insight Into Arctic Ecosystem Change

Global Change Biology Communications, Volume 1, Issue 3, September 2026.
Long‐term chronologies constructed from individual bowhead baleen plates reveal stable isotope declines consistent with regional Arctic food web or productivity changes superimposed on global anthropogenic C and N inputs, while relatively stable hormone concentrations over the same period provide no evidence of a concomitant increase in physiological ...
Cory J. D. Matthews, Justine M. Hudson, Nadine S. J. Lysiak, Kathleen E. Hunt, Mads Peter Heide‐Jørgensen, Steven H. Ferguson   +5 more
wiley   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source