Results 151 to 160 of about 4,471,539 (245)

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Investigations of the Mechanisms of Diabetes Remission: A Focus on Adaptive Thermogenesis [PDF]

, 2019
Background The prevalence of diabetes and obesity have continued to rise over the last 30 years. In New Zealand one in three adults are have obesity and one in twenty have type 2 diabetes mellitus (T2DM).
Corley, Brian
core   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Adipsin and adipocyte-derived C3aR1 regulate thermogenic fat in a sex-dependent fashion

JCI Insight
Thermogenesis in beige/brown adipose tissues can be leveraged to combat metabolic disorders such as type 2 diabetes and obesity. The complement system plays pleiotropic roles in metabolic homeostasis and organismal energy balance with canonical effects ...
Lunkun Ma, Ankit Gilani, Alfonso Rubio-Navarro, Eric Cortada, Ang Li, Shannon M. Reilly, Liling Tang, James C. Lo   +7 more
doaj   +1 more source

Abcc1 deficiency protects from corticosterone but not cortisol‐induced adiposity and insulin resistance in a sex‐specific manner

The Journal of Physiology, EarlyView.
Abstract figure legend A mouse model of exogenous glucocorticoid (GC) treatment was used to determine (1) if corticosterone induced the same metabolic dysregulation as cortisol, and (2) whether these differences were mediated by the corticosterone‐specific transmembrane exporter Abcc1.
Mhairi A. Paul, Boglarka Nagy, Sofia Laforest, Joanna P. Simpson, William Mungall, Natalie Z. M. Homer, Robert K. Semple, Ruth Andrew, Roland H. Stimson, Mark Nixon   +9 more
wiley   +1 more source

Post-competition recovery in natural physique athletes: body composition, metabolic adaptation, and refeeding responses

Journal of the International Society of Sports Nutrition
Background Post-competition refeeding in physique athletes is poorly understood. We aimed to characterize physiological and psychological changes in natural physique athletes across contest preparation and a 12-week recovery period, and to explore the ...
Claire Buechel, Kate Pumpa, Naroa Etxebarria, Eric R. Helms, Luke Ashton, Lachlan Mitchell, Michelle Minehan   +6 more
doaj   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source

The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia in high‐altitude deer mice (Peromyscus maniculatus)

The Journal of Physiology, EarlyView.
Abstract figure legend The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia has been contentious. Many high‐altitude natives have greater haemoglobin–O2 affinity (lower P50, the O2 pressure at 50% haemoglobin saturation) than their low‐altitude counterparts, but the advantages of this change for aerobic metabolism have often remained
Kayla M. Garvey, Graham R. Scott
wiley   +1 more source

Advances in research on thermogenic substances

Journal of Physiological Anthropology
In mammals, a constant body temperature is maintained for survival in cold environments, primarily through the activation of thermogenic mechanisms. In this review, we discussed the advances in research on cold-adaptive thermogenic substances and their ...
Mengdi Tao, Yutong Gao, Xuxia Chai, Jiahui Peng, Changjiang Guo, Lixia Yu, Zhanxin Yao   +6 more
doaj   +1 more source

Cold-induced adaptive thermogenesis is impaired by exposure of Asian sand dust in mice

The following files contain the raw data to the related paper "Cold-induced adaptive thermogenesis is impaired by exposure of Asian sand dust in mice ...
Bagon, B
core   +1 more source