Results 141 to 150 of about 4,471,539 (245)

A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes [PDF]

open access: yes, 2017
The adipokine adipocyte fatty acid-binding protein (A-FABP) has been implicated in obesity-related cardio-metabolic complications. Here we show that A-FABP increases thermogenesis by promoting the conversion of T4 to T3 in brown adipocytes.
Hoo, Ruby L C   +9 more
core   +1 more source

Exploring lifestyle management in polycystic ovary syndrome through implementation frameworks

open access: yesExperimental Physiology, EarlyView.
Abstract Polyendocrine metabolic ovarian syndrome [PMOS; previously known as polycystic ovary syndrome (PCOS)] is an endocrine condition affecting 10%–13% of women of reproductive age, with cardiometabolic, reproductive and psychological features. The PMOS guidelines have established recommendations for its management, which can include pharmacological,
Margaret McGowan   +4 more
wiley   +1 more source

Adaptive Thermogenesis and Metabolic Changes Following Diet- and Exercise-induced Weight Loss [PDF]

open access: yes, 2017
With more than two-thirds of adults in the United States considered as overweight or obese, a myriad of weight loss programs and products that promise quick results have infiltrated the market.
Martin, Alexandra R.
core  

Seven days of warm‐water immersion enhances resting irisin and BDNF, but not klotho, in older men

open access: yesExperimental Physiology, EarlyView.
Abstract We examined whether seven consecutive days of warm‐water immersion could elevate resting and exercise‐induced levels of brain‐derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and metabolic health, but their levels decline with age.
Joel M Garrett   +6 more
wiley   +1 more source

Adaptive thermogenesis in human body weight regulation: more of a concept than a measurable entity? [PDF]

open access: yes, 2012
According to Lavoisier, ‘Life is combustion’. But to what extent humans adapt to changes in food intake through adaptive thermogenesis – by turning down the rate of heat production during energy deficit (so as to conserve energy) or turning it up during ...
Dulloo, Abdul G.   +3 more
core  

Adaptive facultative diet-induced thermogenesis in wild-type but not in UCP1-ablated mice

open access: yes, 2017
The significance of diet-induced thermogenesis (DIT) for metabolic control is still debated. Although obesogenic diets recruit UCP1 and adrenergically inducible thermogenesis, and although the absence of UCP1 may promote the development of obesity, no ...
Nedergaard, Jan,   +7 more
core   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

open access: yesExperimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak   +3 more
wiley   +1 more source

The cold‐water immersion recovery–adaptation paradox: Reconciling acute parasympathetic and analgesic benefits with chronic hypertrophy attenuation

open access: yesExperimental Physiology, EarlyView.
Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera   +8 more
wiley   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga   +8 more
wiley   +1 more source

A MECHANISM OF CELLULAR THERMOGENESIS IN COLD-ADAPTATION [PDF]

open access: yesProceedings of the National Academy of Sciences, 1958
R E, Smith, A S, Fairhurst
openaire   +2 more sources

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