Results 111 to 120 of about 2,045,959 (299)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Terminal power control method of power line carrier communication network based on adaptive hash function

open access: yesDianxin kexue, 2023
In the control of network terminal power, due to the overall low analysis of network state, the adaptive regulation ability of communication network terminal power is poor.Therefore, the power line carrier communication network terminal power control ...
Hong XUE   +4 more
doaj   +2 more sources

On the Potential Use of Adaptive Control Methods for Improving Adaptive Natural Resource Management [PDF]

open access: yes
The paradigm of adaptive natural resource management (AM), in which experiments are used to learn about uncertain aspects of natural systems, is gaining prominence as the preferred technique for administration of large-scale environmental projects.
Bond, Craig A.
core   +1 more source

Use of statistical outlier detection method in adaptive evolutionary algorithms

open access: yes, 2006
In this paper, the issue of adapting probabilities for Evolutionary Algorithm (EA) search operators is revisited. A framework is devised for distinguishing between measurements of performance and the interpretation of those measurements for purposes of ...
Pham, Tuan Q.   +2 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Use of Statistical Outlier Detection Method in Adaptive\ud Evolutionary Algorithms [PDF]

open access: yes, 2006
In this paper, the issue of adapting probabilities for Evolutionary Algorithm (EA) search operators is revisited. A framework is devised for distinguishing between measurements of performance and the interpretation of those measurements for purposes of ...
Pham, Dr Tuan Q.   +2 more
core  

Adaptive Pseudo-Transient-Continuation-Galerkin Methods for Semilinear Elliptic Partial Differential Equations

open access: yes, 2016
In this paper we investigate the application of pseudo-transient-continuation (PTC) schemes for the numerical solution of semilinear elliptic partial differential equations, with possible singular perturbations.
Alaoui   +23 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Stability under learning: the neo-classical growth problem [PDF]

open access: yes
A local stability condition for the standard neo-classical Ramsey growth model is derived. The proposed setting is deterministic, defined in discrete time and expectations are formed through adaptive learning.
Orlando Gomes
core  

Adaptive hybrid optimization strategy for calibration and parameter estimation of physical models

open access: yes, 2011
A new adaptive hybrid optimization strategy, entitled squads, is proposed for complex inverse analysis of computationally intensive physical models. The new strategy is designed to be computationally efficient and robust in identification of the global ...
Atmadji   +35 more
core   +1 more source

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