Results 151 to 160 of about 4,973 (174)

Adar1 restricts line-1 retrotransposition

2017
Adenosine deaminases acting on RNA (ADARs) are enzymes that catalyze the hydrolytic deamination of Adenosine (A) to Inosine (I) (AàI) in double-stranded RNA (dsRNA) substrates. This process is called RNA editing. In literature there are many studies describing ADAR1 as regulator of the replication of different viruses, exerting either a proviral or ...
openaire   +2 more sources

ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

Cell Reports, 2021
Rajendra Karki, SangJoon Lee, Parimal Samir   +2 more
exaly  

Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1

Immunity, 2021
Jorge Henao-Mejia, Carmela Sidrauski, Daniel B Stetson   +2 more
exaly  

ADAR1 regulates vascular remodeling in hypoxic pulmonary hypertension through 1-methyladenosine modification of circCDK17

Acta Pharmaceutica Sinica B, 2023
Jun Fan, Xu-Sheng Yang, Xiaowei Nie
exaly  

Development of Inhibitors of ADAR1

Chemistry and Chemical ...
openaire   +1 more source

Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses

Immunity, 2021
Rachel E Rigby, Tiong Kit Tan, George R Young   +2 more
exaly  

Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms

Proceedings of the National Academy of Sciences of the United States of America, 2021
William M Schneider, Brian Hurwitz, Jiayi Wang   +2 more
exaly  

RNA Editing Enzyme ADAR1 Regulates METTL3 in an Editing Dependent Manner to Promote Breast Cancer Progression via METTL3/ARHGAP5/YTHDF1 Axis

International Journal of Molecular Sciences, 2022
Sheng-Yong Yang, Yi Li
exaly  

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown

Cell, 2018
Xianfang Wu, Brad R Rosenberg, Tony Sun
exaly  

ADAR1 is required for differentiation and neural induction by regulating microRNA processing in a catalytically independent manner

Cell Research, 2015
Jian-Feng Xiang, Li Yang, Ling-Ling Chen
exaly