Results 131 to 140 of about 8,092 (217)

ARID1A loss promotes RNA editing of CDK13 in an ADAR1-dependent manner

BMC Biology
Background ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, is thought to play a significant role both in tumor suppression and tumor initiation, which is highly dependent upon context. Previous studies have suggested that ARID1A deficiency
Tianyu Zhu, Qian Li, Zhe Zhang, Jiahao Shi, Yongyun Li, Feng Zhang, Lingjie Li, Xin Song, Jianfeng Shen, Renbing Jia   +9 more
doaj   +1 more source

RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence [PDF]

, 2018
The double-stranded RNA binding domain (dsRBD) is a small protein domain of 65-70 amino acids adopting an αβββα fold, whose central property is to bind to double-stranded RNA (dsRNA).
Allain, Frédéric, Barraud, Pierre, Masliah, Grégoire   +2 more
core  

RNA editing regulates host immune response and T cell homeostasis in SARS-CoV-2 infection.

PLoS ONE
Adenosine to inosine (A-to-I) RNA editing by ADAR1 has been implicated in maintaining self-tolerance, preventing autoimmunity, and mediating antiviral immunity.
Molly Huang, Adam Mark, Jessica Pham, Karina Vera, Amanda M Saravia-Butler, Afshin Beheshti, Qingfei Jiang, Kathleen M Fisch   +7 more
doaj   +1 more source

ADAR1 expression is associated with cervical cancer progression and negatively regulates NK cell activity

JCI Insight
ADAR1 edits double-stranded RNAs (dsRNAs) by deaminating adenosines into inosines, preventing aberrant activation of innate immunity by endogenous dsRNAs, which may resemble viral structures.
Valentina Tassinari, Marta Kaciulis, Stefano Petrai, Helena Stabile, Angelina Pernazza, Martina Leopizzi, Valeria Di Maio, Francesca Belleudi, Danilo Ranieri, Vanessa Mancini, Innocenza Palaia, Federica Tanzi, Ludovica Lospinoso Severini, Silvia Ruggeri, Maria Emanuela Greco, Giovanni Bernardini, Alessandra Zingoni, Marco Cippitelli, Cristina Cerboni, Alessandra Soriani   +19 more
doaj   +1 more source

ADAR1: a mast regulator of aging and immunity

Signal Transduction and Targeted Therapy, 2023
Yigan Zhang, Jinyue Zhang, Yuanchao Xue
openaire   +3 more sources

The origin of the ADAR gene family and animal RNA editing [PDF]

, 2015

core   +1 more source

ADARs have effects beyond RNA editing [PDF]

, 2009
Heale, Bret S E, Keegan, Liam P, O'Connell, Mary A   +2 more
core   +1 more source

Adenosine-to-Inosine (A-to-I) RNA Editing by ADAR1 to Control RNA Sensing in Cardiovascular Disease. [PDF]

Arterioscler Thromb Vasc Biol
Weldy CS, Li JB, Quertermous T.
europepmc   +1 more source

Exogenous Epstein-Barr virus nuclear antigen 1 induces ADAR1-driven tumor resistance against immunotherapy. [PDF]

Signal Transduct Target Ther
Liu C, Sun Z, Li C, Zhou Y, Gao X, Zhong Y, Luo X, Wang C, Zhang Y, Ni C, Peng M, Jian W, Yang Y, Zhang X, Ren Y, Gong X, Zhao M, Guo X, Cheng C, Chen J, Li X.   +20 more
europepmc   +1 more source

Structural and mechanistic basis of ADAR1-mediated RNA editing and immune regulation. [PDF]

Cell Insight
Deng X, Elsharkawy M, Gao Y.
europepmc   +1 more source