Results 121 to 130 of about 4,773 (159)

Molecular Context of ADAR-Mediated Editing of Coding RNA in Colorectal and Lung Cancers. [PDF]

Int J Mol Sci
Modestov A, Luppov D, Gaziev I, Golushko N, Zakharova G, Zolotovskaia M, Poddubskaya E, Seryakov A, Prassolov V, Sekacheva M, Buzdin A.   +10 more
europepmc   +1 more source

TSniffer: unbiased de novo identification of RNA editing sites and quantification of editing activity in RNA-seq data. [PDF]

Genome Biol
Herrmann M, Krebs Y, Acosta FM, Parusel S, Siering O, Andres FGM, Taye B, Miskey C, Pfaller CK.   +8 more
europepmc   +1 more source

A New Model of Gastric Pre-neoplasia Induced by Aberrant ADAR1-mediated Double-stranded RNA Signaling. [PDF]

Cell Mol Gastroenterol Hepatol
Halstead AM, Nwokolo C, Hoft S, Yu J, Zhu L, Tuley B, Vargas N, Liu R, Victorino FR, Phatak S, Beatty W, Chen CK, DiPaolo R, Cliften P, Bigley TM, Sáenz JB.   +15 more
europepmc   +1 more source

Deficiency of Smooth Muscle Adar1 Exacerbates Vascular Remodeling and Pulmonary Hypertension. [PDF]

Circ Res
Kim Y, Maroli G, Woodcock CC, Kim H, Liu Y, Klouda T, Li Y, Li Q, Hao Y, Schumacher V, Turton HA, Thompson AAR, Looso M, Kuenne C, Valasarajan C, Ruppert C, Avolio T, Tang Y, Tai YY, Kudryashova TV, Goncharova EA, Wu JC, Li JB, Bertero T, Savai R, Raby BA, Chan SY, Pullamsetti SS, Yuan K.   +28 more
europepmc   +1 more source

Role of ADAR1 in Sepsis and Research Progress

Advances in Clinical Medicine
openaire   +1 more source

Investigating the impact of ADAR1 on HCV replication

Kubů, Martin, Roučová, Kristina, Pospíšek, Martin, Vopálenský, Václav   +3 more
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Loss of ADAR1 induces ferroptosis of breast cancer cells

Cellular Signalling
Adenosine deaminases acting on RNA 1(ADAR1), an RNA editing enzyme that converts adenosine to inosine by deamination in double-stranded RNAs, plays an important role in occurrence and progression of various types of cancer. Ferroptosis has emerged as a hot topic of cancer research in recent years.
Chuan, Yin, Meng-Meng, Zhang, Guo-Liang, Wang, Xiao-Yan, Deng, Zeng, Tu, Shan-Shan, Jiang, Zheng-Dan, Gao, Meng, Hao, Yong, Chen, Yi, Li, Sheng-Yong, Yang   +10 more
exaly   +3 more sources

ADAR1 and its implications in cancer development and treatment

Trends in Genetics, 2022
The family of adenosine deaminases acting on RNA (ADARs) regulates global gene expression output by catalyzing adenosine-to-inosine (A-to-I) editing of double-stranded RNA (dsRNA) and through interacting with RNA and other proteins. ADARs play important roles in development and disease, including an increasing connection to cancer progression.
Allison R, Baker, Frank J, Slack
openaire   +2 more sources

ADAR1 mutation causes ZBP1-dependent immunopathology

Nature, 2022
The RNA-editing enzyme ADAR1 is essential for the suppression of innate immune activation and pathology caused by aberrant recognition of self-RNA, a role it carries out by disrupting the duplex structure of endogenous double-stranded RNA species1,2. A point mutation in the sequence encoding the Z-DNA-binding domain (ZBD) of ADAR1 is associated with ...
Nicholas W. Hubbard, Joshua M. Ames, Megan Maurano, Lan H. Chu, Kim Y. Somfleth, Nandan S. Gokhale, Margo Werner, Jessica M. Snyder, Katrina Lichauco, Ram Savan, Daniel B. Stetson, Andrew Oberst   +11 more
openaire   +2 more sources

ADAR1 edits the SenZ and SenZ-ability of RNA

Immunity, 2021
Some RNAs can assume a Z conformation, an unusual, left-handed turn. In this issue of Immunity, three studies report that mutations in the Zα-RNA binding domain of the adenosine deaminase ADAR1 are sufficient to induce autoinflammatory disease in mice, which models human Aicardí-Goutières syndrome, highlighting the important role of Z-RNA editing in ...
Thomas, Zillinger, Eva, Bartok
openaire   +2 more sources