Results 141 to 150 of about 4,773 (159)

Development of Inhibitors of ADAR1

Chemistry and Chemical ...
openaire   +1 more source

Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms

Proceedings of the National Academy of Sciences of the United States of America, 2021
Tony Sun, Yingpu Yu, Xianfang Wu
exaly  

Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy

Immunity, 2021
Taisuke Nakahama, Yuki Kato, Toshiharu Shibuya   +2 more
exaly  

ADAR1 Regulates Lipid Remodeling to Dictate Ferroptosis Sensitivity

Summary Triple-negative breast cancer (TNBC), defined by the lack of estrogen, progesterone, and HER2 receptor expressions, is aggressive and lacks targeted treatment options. Adenosine deaminase acting on RNA 1 (ADAR1) has been shown to contribute to TNBC tumorigenesis by modulating an innate immune response.
Che-Pei, Kung, Nick D, Terzich, Ma Xenia G, Ilagan, Michael J, Prinsen, Madhurima, Kaushal, Raleigh D, Kladney, Jade H, Weber, Alex R, Mabry, Luisangely Soto, Torres, Emily R, Bramel, Eric C, Freeman, Thwisha, Sabloak, Sua, Ryu, William M, Weber, Kyle A, Cottrell, Leonard B, Maggi, Leah P, Shriver, Gary J, Patti, Jason D, Weber   +18 more
openaire   +2 more sources

RNA Editing Enzyme ADAR1 Regulates METTL3 in an Editing Dependent Manner to Promote Breast Cancer Progression via METTL3/ARHGAP5/YTHDF1 Axis

International Journal of Molecular Sciences, 2022
Yi Li, Sheng-Yong Yang
exaly  

The role of RNA editing enzyme ADAR1 in human disease

Wiley Interdisciplinary Reviews RNA, 2022
Brian Song, Yusuke Shiromoto, Kazuko Nishikura   +2 more
exaly  

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown

Cell, 2018
Hachung Chung, Xianfang Wu, Tony Sun
exaly  

ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress

Cell Stem Cell, 2020
Diana Guallar, Alejandro Fuentes-Iglesias, Cristina Ameneiro   +2 more
exaly  

ADAR1 is required for differentiation and neural induction by regulating microRNA processing in a catalytically independent manner

Cell Research, 2015
Jian-Feng Xiang, Shanshan Zhu, Qing-Fei Yin   +2 more
exaly  

ADAR1 regulates Mda5-MAVS

Nature Immunology, 2015
openaire   +1 more source