Results 141 to 150 of about 2,950 (156)
The RNA editing enzyme ADAR2 restricts L1 mobility [PDF]
RNA Biology, 2021 adenosine deaminases acting on RNA (ADARs) are enzymes that convert adenosines to inosines in double-stranded RNAs (RNA editing A-to-I). ADAR1 and ADAR2 were previously reported as HIV-1 proviral factors.
Margherita Doria +2 more
exaly +4 more sources
Oncogene, 2012 Grade IV astrocytoma or glioblastoma multiforme (GBM) is one of the most aggressive and lethal tumors affecting humans. ADAR2-mediated A-to-I RNA editing, an essential post-transcriptional modification event in brain, is impaired in GBMs and astrocytoma ...
Loredana Cifaldi +2 more
exaly +4 more sources
Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects [PDF]
EMBO Journal, 2011 ADAR2 catalyses the deamination of adenosine to inosine at the GluR2 Q/R site in the pre-mRNA encoding the critical subunit of AMPA receptors. Among ADAR2 substrates this is the vital one as editing at this position is indispensable for normal brain ...
Liam Keegan +2 more
exaly +2 more sources
Altered Intracellular Milieu of ADAR2-Deficient Motor Neurons in Amyotrophic Lateral Sclerosis
Genes, 2017 Transactive response DNA-binding protein (TDP-43) pathology, and failure of A-to-I conversion (RNA editing) at the glutamine/arginine (Q/R) site of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor subunit GluA2, are etiology-linked ...
Megumi Akamatsu +2 more
exaly +2 more sources
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Exercise-Induced ADAR2 Protects against Nonalcoholic Fatty Liver Disease through miR-34a
Nutrients, 2023Changqing Yang, Yaru Zhu
exaly
ADAR2-dependent A-to-I RNA editing in the extracellular linear and circular RNAs
Neuroscience Research, 2019Akira Tamaoka, Naoki Hirose, Shin Kwak
exaly