Results 161 to 170 of about 15,493 (211)

ADAR Gene Family and A-to-I RNA Editing: Diverse Roles in Posttranscriptional Gene Regulation

2005
Publisher Summary The biological process of A-to-I RNA editing mediated by ADAR is discussed with new directions on potentially novel targets, including the widely expressed Alu retrotransposable elements found in noncoding regions of mRNA. Many events take place after the de novo synthesis of an RNA transcript, leading to alterations from its gene ...
Louis, Valente, Kazuko, Nishikura
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[Analysis of ADAR gene mutations in two pedigrees affected with dyschromatosis symmetrica hereditaria].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2019
To detect mutations of ADAR gene in two pedigrees affected with dyschromatosis symmetrica hereditaria (DSH).Potential mutations of the ADAR gene were analyzed by Sanger sequencing of the probands from both pedigrees. Suspected mutations were validated by Sanger sequencing of other patients from both pedigrees as well as unrelated healthy individuals.A ...
Zhenhua Zhao, Conghui Wang, Xiangdong Kong   +2 more
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A novel frameshift mutation of the ADAR1 gene in a Chinese patient with dyschromatosis symmetrica hereditaria and the dermoscopic features

Journal of the European Academy of Dermatology and Venereology, 2017
Dyschromatosis symmetrica hereditaria (DSH), which characterized by hyper- or hypopigmented macules on the dorsal aspect of distal extremities and freckle-like macules on the face, is a rare pigmented genodermatosis that usually restricted to the skin.
Cheng Chi, Yixin Luo, Jie Liu
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Two novel mutations and evidence for haploinsufficiency of the ADAR gene in dyschromatosis symmetrica hereditaria

British Journal of Dermatology, 2006
Q. Liu, Luo Jiang, W.‐L. Liu, X-J. Kang, Ao Yang, Miao Sun, Yang Luo, Yong Song, Wilson H.Y. Lo, Xinan Zhang   +9 more
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A frameshift mutation in the ADAR gene in a Korean family with dyschromatosis symmetrica hereditaria

European Journal of Dermatology, 2014
Dyschromatosis symmetrica hereditaria (DSH; MIM 127400) is a rare autosomal dominant skin disorder characterized by a mixture of hyper- and hypopigmented macules on the dorsal surface of the extremities and face. Onset of the disease is usually during infancy or early childhood. Dyschromatosis stops spreading before adolescence and lasts for life.
Young Bok Lee, Seung Bok Lee, Su Jin Kim, Sae Mi Park, Hye Rim Ko, Jin-Wou Kim, Dong Soo Yu   +6 more
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A novel nonsense mutation of ADAR1 gene in a Chinese patient with dyschromatosis symmetrica hereditaria

Journal of the European Academy of Dermatology and Venereology, 2014
Qiuyue Wu, Weiwei Li, Na Li, Tao Li, C. Zhang, Tianming Ni, Yue Cui, Xinjun Li, Xinyi Xia   +8 more
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F11R RNA trinucleotide over-edited by ADAR in gastric and colorectal cancers: Cross-cohort validation, gene expression regulation, and diagnostic significance

Biochemical and Biophysical Research Communications
The F11 receptor (F11R) gene encoding junctional adhesion molecule A has been associated with gastric cancer (GC) and colorectal cancer (CRC), in which its role and regulation remain to be further elucidated. Recently F11R was also identified as a potential target of adenosine-to-inosine (A-to-I) mediated by the adenosine deaminases acting on RNA ...
Chuanqing Bao, Jun-Jie Feng, Jing Cui, Tao Guo, Yu-Shan He, Zhi-Yuan Wei, Chengjia Qian, Yunyun Jin, Jian‐Huan Chen   +8 more
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A novel splice site mutation in theADARgene leading to exon skipping and dyschromatosis symmetrica hereditaria in a Japanese patient

Clinical and Experimental Dermatology, 2016
Osamu Ansai, Yohya Shigehara, Akiko Ito, Riichiro Abe, Yutaka Shimomura   +4 more
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Insights into ADAR gene complement, expression patterns, and RNA editing landscape in Chlamys farreri

Fish & Shellfish Immunology
Adenosine Deaminases Acting on RNA (ADARs) are evolutionarily conserved enzymes known to convert adenosine to inosine in double-stranded RNAs and participate in host-virus interactions. Conducting a meta-analysis of available transcriptome data, we identified and characterised eight ADAR transcripts in Chlamys farreri, a farmed marine scallop ...
Enrico Bortoletto, Umberto Rosani, Akari Sakaguchi, Jeongwoong Yoon, Kazue Nagasawa, Paola Venier   +5 more
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A novel missense mutation of $$\textit{ADAR1}$$ ADAR 1 gene in a Chinese family leading to dyschromatosis symmetrica hereditaria and literature review

Journal of Genetics, 2017
Shuai-Mei Liu, Mengxia Ni, Mingchao Zhang, Peiran Zhu, Qiuyu Wu, Weijun Jiang, Jing Zhang, Weiwei Li, Xinyi Xia   +8 more
openalex   +2 more sources