ADAR expression and copy number variation in patients with advanced gastric cancer [PDF]
, 2020 Javad Behroozi +3 more
openalex +1 more source
Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections
Advanced Science, Volume 13, Issue 3, 14 January 2026.This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin +3 more
wiley +1 more source
Alu Overexpression Leads to an Increased Double‐Stranded RNA Signature in Dermatomyositis
Arthritis &Rheumatology, Volume 78, Issue 1, Page 209-222, January 2026.Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the noncoding genome in disease pathogenesis.
Rayan Najjar +2 more
wiley +1 more source
RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling [PDF]
, 2013 The Hedgehog (HH) signaling pathway has important roles in tumorigenesis and in embryonal patterning. The Gliomaassociated oncogene 1 (GLI1) is a key molecule in HH signaling, acting as a transcriptional effector and, moreover, is considered to be a ...
Mohammed Ferdous-Ur, Rahman +7 more
core +1 more source
Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis
Redox Biology, 2018 Alterations in microRNA (miRNA) processing have been previously linked to aging. Here we used the small molecule enoxacin to pharmacologically interfere with miRNA biogenesis and study how it affects aging in C. elegans.
Silas Pinto +13 more
doaj +1 more source
The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]
, 2014 Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, Nicky J. +3 more
core +2 more sources
The Nefarious Nexus of Noncoding RNAs in Cancer [PDF]
, 2018 The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts.
Anastasiadou, Eleni +3 more
core +1 more source
Cell Reports, 2014 Inadequate adenosine-to-inosine editing of noncoding regions occurs in disease but is often uncorrelated with ADAR levels, underscoring the need to study deaminase-independent control of editing. C.
Michael C. Washburn +6 more
doaj +1 more source
Esquema de integración para experimentación real con sistemas robóticos bi-brazo [PDF]
, 2016 En este art culo se presenta un esquema para la integraci on de un sistema rob otico bi-brazo, para transformar resultados obtenidos de simulaciones en ejecuciones en un entornos real. Este esquema utiliza una capa de comunicaci on basada en \The Robot
Rodríguez Pacheco, Carlos +2 more
core
Multiple roles of ADAR-dependent RNA editing in mesothelioma
, 2022 Emanuela Felley‐Bosco +1 more
openalex +1 more source