Results 111 to 120 of about 4,312 (239)

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy [PDF]

, 2020
Anzer Khan, Simona Paro, Leeanne McGurk, Nagraj Sambrani, Marion C. Hogg, James Brindle, Giuseppa Pennetta, Liam P. Keegan, Mary A. O’Connell   +8 more
openalex   +1 more source

Hairpin RNA: a secondary structure of primary importance [PDF]

, 2018
.: An RNA hairpin is an essential secondary structure of RNA. It can guide RNA folding, determine interactions in a ribozyme, protect messenger RNA (mRNA) from degradation, serve as a recognition motif for RNA binding proteins or act as a substrate for ...
Cara, A., Svoboda, P.
core  

Clinical significance, tumor immune landscape and immunotherapy responses of ADAR in pan-cancer and its association with proliferation and metastasis of bladder cancer [PDF]

, 2023
Hao Yu, Kexin Bai, Yidong Cheng, Jiancheng Lv, Qiang Song, Haiwei Yang, Qiang Lü, Xiao Yang   +7 more
openalex   +1 more source

Modulation of ADARs mRNA expression in congenital heart defect patients [PDF]

, 2018
Faizah Altaf, Cornelia Vesely, Abdul Malik Sheikh, Rubab Munir, Syed Tahir Abbass Shah, Aamira Tariq   +5 more
openalex   +1 more source

Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus

Cell Reports, 2018
Summary: RNA-editing mechanisms, which induce nucleotide substitution in the RNA, increase transcript and protein diversities. Editing dysregulation has been shown to lead to grave outcomes, and transcriptome-wide aberrant RNA editing has been found in ...
Shalom Hillel Roth, Miri Danan-Gotthold, Meirav Ben-Izhak, Gideon Rechavi, Cyrille J. Cohen, Yoram Louzoun, Erez Y. Levanon   +6 more
doaj   +1 more source

dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells [PDF]

, 2017
Double-stranded RNA (dsRNA) can enter different pathways in mammalian cells, including sequence-specific RNA interference (RNAi), sequence-independent interferon (IFN) response and editing by adenosine deaminases.
Filipowicz, Witold, Filkowski, Jody, Flemr, Matyas, Malik, Radek, Nejepinska, Jana, Svoboda, Petr   +5 more
core  

A-to-I-edited miR-1251-5p restrains tumor growth and metastasis in lung adenocarcinoma through regulating TCF7-mediated Wnt signaling pathway

Discover Oncology
Background RNA editing from A (adenine nucleotide) to I (hypoxanthine nucleotide) mediated by ADARs has attracted more and more attention as an important post-transcriptional processing method.
Shuhua Xu, Guoping Zhou, Qiyu He, Junning Ding, Xiaoli Liu, Youshuang Cheng, Yaqing Shen   +6 more
doaj   +1 more source

Effect of SNORD113-3/ADAR2 on glycolipid metabolism in glioblastoma via A-to-I editing of PHKA2

Cellular & Molecular Biology Letters
Background Glioblastoma multiforme (GBM) is a highly aggressive brain tumor, characterized by its poor prognosis. Glycolipid metabolism is strongly associated with GBM development and malignant behavior.
Zheng Cui, Xiaobai Liu, Tiange E, Hongda Lin, Di Wang, Yunhui Liu, Xuelei Ruan, Ping Wang, Libo Liu, Yixue Xue   +9 more
doaj   +1 more source

ADARs employ a neural-specific mechanism to regulate PQM-1 expression and survival from hypoxia [PDF]

, 2023
Ananya Mahapatra, Alfa Dhakal, Aika Noguchi, Pranathi Vadlamani, Heather A. Hundley   +4 more
openalex   +1 more source

Phylogenetic and structural analysis of Hydra ADAR

Archives of Biochemistry and Biophysics
Adenosine deaminases acting on RNAs (ADARs) perform adenosine-to-inosine (A-to-I) RNA editing for essential biological functions. While studies of editing sites in diverse animals have revealed unique biological roles of ADAR editing including temperature adaptation and reproductive maturation, rigorous biochemical and structural studies of these ADARs
Xander E. Wilcox, Howard Zhang, Jasmine L. Mah, Jack F. Cazet, Sukanya Mozumder, Srinidhi Venkatesh, Celina E. Juliano, Peter A. Beal, Andrew J. Fisher   +8 more
openaire   +3 more sources