Results 41 to 50 of about 4,312 (239)

The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis

eLife, 2017
ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date.
Sarah N Deffit, Brian A Yee, Aidan C Manning, Suba Rajendren, Pranathi Vadlamani, Emily C Wheeler, Alain Domissy, Michael C Washburn, Gene W Yeo, Heather A Hundley   +9 more
doaj   +1 more source

A-to-I RNA editing in the earliest-diverging Eumetazoan phyla [PDF]

, 2017
© The Author(s), 2017. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Molecular Biology and Evolution 34 (2017): 1890-1901, doi:10.1093/molbev/msx125.The highly conserved ...
Alon, Shahar, Eisenberg, Eli, Kaniewska, Paulina, Levanon, Erez, Levy, Oren, Porath, Hagit T., Rosenthal, Joshua J. C., Schaffer, Amos A.   +7 more
core   +1 more source

Shountrade, Adare

, 1937
Creagán na hOla Graveyard in the Parish of Adare / Murphy, Kitty -- How Creagán na hOla Got Its Name / Murphy, Kitty -- Creagán na hOla / Hickey, Mary -- Desmonds' Castle, Adare / Hickey, Mary -- St Brigid's Well / Fennell, Brigid -- My School District - Shountrade / Fennell, Brigid -- Seanbheann, Rour, Adare / Monckton, Mary -- Old Relic of the Fenian
Shountrade, Adare, Fhloinn, Máire, Murphy, Kitty, Hickey, Mary, Fennell, Brigid, Monckton, Mary, Monckton, Kathryn, Kinevane, Annie, Bourke, Kitty, Dillon, Chrissie, Conway, Nora, Browne, Nora, Fennell, Thomas, Bourke, Mary, Bourke, Stephen, Nash, Peggy, Mahon, Thomas Mc   +16 more
openaire   +1 more source

Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs

Genome Biology, 2017
One of the most prevalent forms of post-transcritpional RNA modification is the conversion of adenosine nucleosides to inosine (A-to-I), mediated by the ADAR family of enzymes.
Carl R. Walkley, Jin Billy Li
doaj   +1 more source

Population and allelic variation of A-to-I RNA editing in human transcriptomes. [PDF]

, 2017
BackgroundA-to-I RNA editing is an important step in RNA processing in which specific adenosines in some RNA molecules are post-transcriptionally modified to inosines.
Demirdjian, Levon, Guo, Jiguang, Lin, Lan, Park, Eddie, Shen, Shihao, Wu, Ying Nian, Xing, Yi   +6 more
core   +2 more sources

Adare Convent

, 1937
A collection of folklore and local history stories from Adare Convent (school) (Adare, Co. Limerick), collected as part of the Schools' Folklore Scheme, 1937-1938 under the supervision of teacher An tSr. Mechtildes.
Adare Convent, Mechtildes, , Scanlon, Brigid, Carthy, Pauline Mc, Sheehan, Teresa, Connolly, Mona, Sheehan, Theresa, Wilson, Charlotte, Fitzgerald, Brigid, Fitzgerald, B., Mhíonachain, Máire Ní, Mhíonacháin, Máire Ní, Tydings, Mary, Allen, Mary, Stokes, Maura, Sheehan, Nora, Hanly, Annie, Burke, Nancy, Bourke, Nancy, Hanley, Annie, Scanlon, Annie, Hourigan, Rita, Moloney, Nancy, SMM   +23 more
openaire   +1 more source

Activity-regulated RNA editing in select neuronal subfields in hippocampus [PDF]

, 2012
RNA editing by adensosine deaminases is a widespread mechanism to alter genetic information in metazoa. In addition to modifications in non-coding regions, editing contributes to diversification of protein function, in analogy to alternative splicing ...
Ales Balik, Altschul, Andrew C. Penn, Aruscavage, Bass, Birney, Bratt, Brorson, Coleman, Coleman, Daniel, Darty, Dawson, de la Mata, Feldmeyer, Feng, Fisahn, Gahwiler, Gainey, Gallo, Ge, Goodman, Greger, Greger, Greger, Gurevich, Hamada, Hideyama, Hideyama, Higuchi, Higuchi, Hoopengardner, Hundley, Ingo H. Greger, Jepson, Katoh, Kent, Lee, Lein, Li, Liu, Lomeli, Maas, Marcucci, Palladino, Paul, Peng, Peng, Penn, Penn, Penn, Pozo, Rosenthal, Rueter, Ryman, Sanjana, Schoft, Seeburg, Seeburg, Sommer, Sommer, Stefl, Stefl, Tariq, Toth, Traynelis, Turrigiano, Turrigiano, Valente, Venkatesh, Wang, Witter, Xie, Zsofia Nemoda   +73 more
core   +1 more source

Squid express conserved ADAR orthologs that possess novel features. [PDF]

Front Genome Ed, 2023
Vallecillo-Viejo IC, Voss G, Albertin CB, Liscovitch-Brauer N, Eisenberg E, Rosenthal JJC.   +5 more
europepmc   +3 more sources

ADAR1 is a new target of METTL3 and plays a pro-oncogenic role in glioblastoma by an editing-independent mechanism

Genome Biology, 2021
Background N 6 -methyladenosine (m6A) and adenosine-to-inosine (A-to-I) RNA editing are two of the most abundant RNA modification events affecting adenosines in mammals.
Valentina Tassinari, Valeriana Cesarini, Sara Tomaselli, Zaira Ianniello, Domenico Alessandro Silvestris, Lavinia Ceci Ginistrelli, Maurizio Martini, Biagio De Angelis, Gabriele De Luca, Lucia Ricci Vitiani, Alessandro Fatica, Franco Locatelli, Angela Gallo   +12 more
doaj   +1 more source

Adar is essential for optimal presynaptic function [PDF]

Molecular and Cellular Neuroscience, 2013
RNA editing is a powerful way to recode genetic information. Because it potentially affects RNA targets that are predominantly present in neurons, it is widely hypothesized to affect neuronal structure and physiology. Across phyla, loss of the enzyme responsible for RNA editing, Adar, leads to behavioral changes, impaired locomotion, neurodegeneration ...
Carolina, Maldonado, Daniel, Alicea, Maryvi, Gonzalez, Maria, Bykhovskaia, Bruno, Marie   +4 more
openaire   +2 more sources