Results 191 to 200 of about 345,011 (278)

Outcomes and risk factors of hemorrhage in patients with resected brain metastases

International Journal of Cancer, EarlyView.
What's New? Brain metastases may present with hemorrhage, yet risk factors and clinical outcomes remain unclear. Based on a cohort of 880 patients with resected brain metastases, this study identified tumor volume and primary tumor histology (melanoma and non‐small cell lung cancer) as key predictors of hemorrhage.
Melisa S. Guelen, Kiarash Ferdowssian, Niklas Jung, Hava N. Celik, Andrea Dell'Orco, Semil Eminovic, Anton Früh, Majd Samman, Güliz Acker, Arend Koch, Helena Radbruch, Michael Scheel, Mike P. Wattjes, Julia Onken, Peter Vajkoczy, Nils Hecht, Jawed Nawabi, David Wasilewski   +17 more
wiley   +1 more source

Magnetic resonance imaging features differentiate histologic and molecular subtypes of glioblastoma IDH-Wild type CNS WHO grade 4. [PDF]

J Neurooncol
Patel SH, Mayorov S, Kim W, Singh K, Loftus JR, Patrie JT, Batchala PP, Ko A, Lee MD, Jain R, Schiff D.   +10 more
europepmc   +1 more source

Cancer risks and trends between 1997 and 2018, and effects of restored immunity in people living with HIV: Results from the ANRS CO4 French hospital database on HIV

International Journal of Cancer, EarlyView.
What's New? This large nation‐wide cohort study provides a comprehensive 20‐year analysis of cancer trends among people living with HIV in France, highlighting persistent excess risks for virus‐related cancers despite effective antiretroviral therapy and immune restoration.
Sophie Grabar, Paula Lakrout, Valérie Potard, Aurélien Belot, Jacques Cadranel, Christine Jacomet, Christine Katlama, Esaïe Marshall, Olivier Lambotte, Romain Palich, Sylvie Ronot‐Bregigeon, Jean‐Philippe Spano, Anne‐Marie Bouvier, Alain Makinson, Dominique Costagliola   +14 more
wiley   +1 more source

Current landscape of sequencing ADCs in metastatic breast cancer. [PDF]

Ther Adv Med Oncol
McLaughlin S, Ravani LV, Moy B, Medford AJ, Isakoff SJ, Liu T, Ellisen LW, Spring LM, Wander SA, Abelman RO.   +9 more
europepmc   +1 more source

Ultrafast in‐memory computing and highly efficient deep neural networks driven by phase‐change memory materials with partially amorphous state transitions

InfoScience, EarlyView.
This work addresses challenges including the nonlinear weight‐conductance update and the trade‐off between increasing melting uniformity and reducing solid‐to‐liquid transition time. It utilizes all four melting states to create an integrated framework for attaining in‐memory computing and deep neural network applications. The framework achieves a near‐
Kian‐Guan Lim, Shao‐Xiang Go, Qiang Wang, Dong‐Gwan Kim, Chan‐Hwi Baek, Qishen Wang, Tae Hoon Lee, Desmond K. Loke   +7 more
wiley   +1 more source

Targeting uPARAP with an Antibody-Drug Conjugate Exhibits Efficacy against Mesothelioma and Synergizes with Cisplatin. [PDF]

Cancer Res Commun
Çakılkaya P, Egeland Larsen IM, Jiang Q, Sandal Nørregaard K, Gårdsvoll H, Zhang J, Jürgensen HJ, Hansen Blomquist M, Martinez Perlado A, Krigslund O, Santoni-Rugiu E, Engelholm LH, Hassan R, Behrendt N.   +13 more
europepmc   +1 more source

Organic neuromorphic electronics powering intelligent sensory and edge computing systems

InfoMat, EarlyView.
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo, Minji Chung, Hyun Woo Song, Seoyoung Kim, Eun Kwang Lee, Joon Hak Oh   +5 more
wiley   +1 more source

The Recycling Collagen Receptor uPARAP Is a Unique Mediator of Stromal Drug Delivery to Carcinoma Cells. [PDF]

Mol Cancer Ther
Nørregaard KS, Larsen IME, Jürgensen HJ, Blomquist MH, Çakilkaya P, Metrangolo V, Perlado AM, Krigslund O, Gårdsvoll H, Poulsen TT, Mumberg D, Santoni-Rugiu E, Engelholm LH, Behrendt N.   +13 more
europepmc   +1 more source

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source