Results 101 to 110 of about 567,714 (357)

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Aluminum with dispersed nanoparticles by laser additive manufacturing. [PDF]

, 2019
While laser-printed metals do not tend to match the mechanical properties and thermal stability of conventionally-processed metals, incorporating and dispersing nanoparticles in them should enhance their performance. However, this remains difficult to do
Cao, Chezheng, Jiang, Lin, Lavernia, Enrique J, Li, Xiaochun, Lin, Ting-Chiang, Schoenung, Julie M, Sokoluk, Maximilian, Wang, Xin   +7 more
core  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Additive Manufacturing of Ceramics [PDF]

eCAADe proceedings, 2019
Additive manufacturing (AM) is vastly developing across the industrial landscape and has recently expanded outside of the traditional polymeric and metallic-based materials. Ceramics are an ever-present material in the architectural field, but there has been minimal evolution in its associated manufacturing processes.
openaire   +2 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Influence of Recoater Speed on Powder Bed and Part Quality in Powder Bed Fusion of Metals Using a Laser Beam

Metals
The powder bed fusion of metals using a laser beam (PBF-LB/M) is an additive manufacturing process for the direct production of metal parts using powder as a starting material.
Nick Hantke, Tim Robert Brocksieper, Tobias Grimm, Jan T. Sehrt   +3 more
doaj   +1 more source

In process monitoring of the thermal profile during solidification in laser directed energy deposition of aluminium

Additive Manufacturing Letters, 2022
The manufacturing of parts in a layer-by-layer fashion in laser based directed energy deposition (L-DED) of wire enables a unique flexibility and freedom of part design, but some technological challenges remain unsolved.
Christian Hagenlocher, Patrick O’Toole, Wei Xu, Milan Brandt, Mark Easton, Andrey Molotnikov   +5 more
doaj  

Additive Manufacturing as a Manufacturing Method: an Implementation Framework for Additive Manufacturing in Supply Chains [PDF]

, 2017
The supply chain is changing speedily and on a continuous basis to keep up with the rapid changes in the market, which are summarized as increased competition, changes in traditional customer bases, and changes in customers’ expectations. Thus, companies
HANDAL, RAED S.I.
core  

Hybrid Additive Manufacturing [PDF]

, 2021
This idea is to combine two basic additive manufacturing technologies, FFF and SLA. The aim of the described process is not to use SLA’s biggest advantage being high print resolution, but to use it as a mere helper to ensure more isotropic properties of ...
Konvicny, Jiri, Rossing, Lars
core   +1 more source