Results 81 to 90 of about 1,538,268 (308)
Journal of Manufacturing and Materials ProcessingSustainable feedstock management remains a major challenge in laser beam powder bed fusion (PBF-LB), where conventional reuse strategies are typically limited to sieving and blending rather than full material regeneration.
Olga Bashmakova +11 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Effect of fluoride ion cleaning on surface state and properties of Ni3Al-base superalloy IC10
Cailiao gongchengAfter turbine blades are in service， the defect surface oxide film will affect the repair quality of vacuum brazing. By cleaning the IC10 alloy with fluoride ion， the effects of fluoride ion cleaning on the removal of oxide film， the changes of surface ...
ZHOU Zizheng +3 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Nature CommunicationsCeramic circuit boards (CCBs) have been extensively utilized in 5G communications, aerospace, and artificial intelligence due to their excellent thermal conductivity and electrical performance. However, due to the limitation of manufacturing technologies,
Guangming Zhang +12 more
doaj +1 more source
Journal of Materials Research and TechnologyLaser Powder Bed Fusion (LPBF) offers a promising approach for creating metallic components with tailored properties. However, low production speed and high manufacturing costs remain challenges.
Mahyar Hasanabadi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Additive Manufacturing: Prospects and Diverse Applications
Additive manufacturing (AM), also known as 3D printing, has emerged as a transformative technology in various industries, providing unprecedented design freedom and customized manufacturing solutions.
Zeyuan Li +6 more
core +1 more source