Results 61 to 70 of about 137,861 (305)

Progress in research and applications of additively manufactured nickel-based superalloy in aero-engines and gas turbines

Journal of Aeronautical Materials
Nickel-based superalloy is an essential material to prepare hot-end components in aero-engines and gas turbines，due to its excellent mechanical properties under high temperature.
WU Yu, CHEN Bingqing, LIU Wei, HUANG Shuai, SUN Bingbing, ZHANG Xuejun, CHEN Pei, HUANG Chen   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A benchmarking part for evaluating and comparing support structures of additive manufacturing

, 2018
Additive manufacturing technology has been rapidly developed and increasingly popular nowadays; its applications spread to almost every corner in our lives.
Zheng, Pai, Xu, Xun, Jiang, Jingchao, Stringer, Jonathan   +3 more
core   +1 more source

Oxidation in wire arc additive manufacturing of aluminium alloys

, 2021
Wire Arc Additive Manufacturing is a near-net-shape machining technology that enables low-cost production of large and customised metal parts. In the present work, oxidation effects in Wire Arc Additive Manufacturing of the aluminium alloy AW4043/AlSi5 ...
Hauser, Tobias,, Reisch, Raven T.,, Breese, Philipp P.,, Nalam, Yogesh,, Bela, Katharina,, Joshi, Kaivalya S.,, Kaplan, Alexander F.H.,, Kamps, Tobias,, Volpp, Joerg,   +8 more
core   +1 more source

Optimum corrosion performance using microstructure design and additive manufacturing process control

npj Materials Degradation
Compatibility of traditional metallic alloys, particularly 316 L stainless steel, with additive manufacturing (AM) processes, is essential for industrial applications.
Parisa Moazzen, Ayda Shahriari, SeyedAmirReza Shamsdini, Payam Seraj, Foroozan Forooghi, Yahya Aghayar, Sajad Shakerin, Mackenzie Remington Purdy, Mohsen Mohammadi   +8 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Design for Additive Manufacturing : Supporting Intrinsic-Motivated Creativity [PDF]

, 2017
Emotional aspects and designers’ motivations in Design For Additive Manufacturing are rarely studied. Still, as they can influence creative behaviors, it is worth of interest to draw some bases for a relation between designers’ motivations and the field ...
VAYRE, Benjamin, ABED, Stéphane, Stéphane Abed, Carole Bouchard, SEGONDS, Frederic, BOUCHARD, Carole, Frédéric Segonds, Benjamin Vayre, RIAS, Anne Lise, Anne-lise Rias   +9 more
core   +1 more source

Design for laser additive manufacturing

, 2022
S.259-279Today, laser additive manufacturing (LAM) is used in many industrial applications. Because of the freedom in design allowed by LAM, it offers much potential for new approaches in product design.
Kranz, J., Herzog, D., Emmelmann, C.
core   +1 more source

Compositional criteria to predict columnar to equiaxed transitions in metal additive manufacturing

Nature Communications
Predicting the columnar to equiaxed transition (CET) and grain refinement for additively manufactured alloys from thermodynamic databases has been a long-standing challenge and an ongoing source of discussion.
Ryan Brooke, Duyao Zhang, Dong Qiu, Mark A. Gibson, Mark Easton   +4 more
doaj   +1 more source