Results 61 to 70 of about 1,538,268 (308)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Investigation into the Development of an Additive Manufacturing Technique for the Production of Fibre Composite Products [PDF]

, 2015
The advancements in manufacturing technology over recent years have made Additive Manufacturing, a breakthrough technology in the designing and manufacturing field.
Birkett, M., Shyha, Islam, Bade, L., Birkett, Martin, Bade, Lokesh, Shyha, I., Hackney, Philip, Hackney, P.M.   +7 more
core   +1 more source

Defect detection by multi-axis infrared process monitoring of laser beam directed energy deposition

Scientific Reports
Laser beam directed energy deposition (DED-LB) is an attractive additive manufacturing technique to produce versatile and complex 3D structures on demand, apply a cladding, or repair local defects.
T. Herzog, M. Brandt, A. Trinchi, A. Sola, C. Hagenlocher, A. Molotnikov   +5 more
doaj   +1 more source

Progress in research and applications of additively manufactured nickel-based superalloy in aero-engines and gas turbines

Journal of Aeronautical Materials
Nickel-based superalloy is an essential material to prepare hot-end components in aero-engines and gas turbines，due to its excellent mechanical properties under high temperature.
WU Yu, CHEN Bingqing, LIU Wei, HUANG Shuai, SUN Bingbing, ZHANG Xuejun, CHEN Pei, HUANG Chen   +7 more
doaj   +1 more source

Modelling and optimising hybrid process of wire arc additive manufacturing and high-pressure rolling

Materials & Design, 2022
Hybrid process of wire arc additive manufacturing (WAAM) and high-pressure rolling can build large-scale components with low detrimental residual stress (RS) and distortion. We developed an efficient coupled process model for a steel wall to simulate the
Valeriy Gornyakov, Yongle Sun, Jialuo Ding, Stewart Williams   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A benchmarking part for evaluating and comparing support structures of additive manufacturing

, 2018
Additive manufacturing technology has been rapidly developed and increasingly popular nowadays; its applications spread to almost every corner in our lives.
Zheng, Pai, Xu, Xun, Jiang, Jingchao, Stringer, Jonathan   +3 more
core   +1 more source

Optimum corrosion performance using microstructure design and additive manufacturing process control

npj Materials Degradation
Compatibility of traditional metallic alloys, particularly 316 L stainless steel, with additive manufacturing (AM) processes, is essential for industrial applications.
Parisa Moazzen, Ayda Shahriari, SeyedAmirReza Shamsdini, Payam Seraj, Foroozan Forooghi, Yahya Aghayar, Sajad Shakerin, Mackenzie Remington Purdy, Mohsen Mohammadi   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Design and Characterization of 2.5D Nature-Inspired Infill Structures under Out-Plane Quasi-Static Loading Condition

Advances in Materials Science and Engineering, 2023
The 2.5D (2.5-dimensional) structures are acquired to enhance safety and lightweight designs with better energy absorption in the aerospace and automobile sectors. Additive manufacturing (AM), which is practical to build suitable components in industrial
Dara Ashok, M. V. A. Raju Bahubalendruni
doaj   +1 more source