Results 61 to 70 of about 1,616,356 (309)

Modelling and optimising hybrid process of wire arc additive manufacturing and high-pressure rolling

Materials & Design, 2022
Hybrid process of wire arc additive manufacturing (WAAM) and high-pressure rolling can build large-scale components with low detrimental residual stress (RS) and distortion. We developed an efficient coupled process model for a steel wall to simulate the
Valeriy Gornyakov, Yongle Sun, Jialuo Ding, Stewart Williams   +3 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Effect of TiB₂ Addition on the Microstructure and Mechanical Properties of Laser-Directed Energy Deposition TiAl Alloy

Metals
The microstructure characteristics of TiAl alloy prepared by laser-directed energy deposition (L-DED) are coarse columnar grains parallel to the building direction, which results in serious mechanical properties and anisotropy and limits its application.
Yancheng Yang, Yi Hu, Hongyan Chen, Yu Li, Jiawei Wang, Xu Cheng, Haibo Tang, Xianzhe Ran, Dong Liu   +8 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

On the Ultrasonic Atomization of SS316L Parts Manufactured via Laser Powder Bed Fusion for the Closed-Loop Production

Journal of Manufacturing and Materials Processing
Sustainable feedstock management remains a major challenge in laser beam powder bed fusion (PBF-LB), where conventional reuse strategies are typically limited to sieving and blending rather than full material regeneration.
Olga Bashmakova, Leonid Fedorenko, Andrey Vasilev, Boris Zotov, Andrey Urzhumtsev, Ali Kavousi Sisi, Maria Lyange, Ivan Pelevin, Mikhail Gilvitinov, Ksenia Petukhova, Ekaterina Zinovyeva, Stanislav Chernyshikhin   +11 more
doaj   +1 more source

Hybridization of materials and processes by additive manufacturing

, 2018
Material hybrids allow for property combinations like electrically conductive/electrically insulating, magnetic/non-magnetic, ductile/hard, porous/non-porous or metallic gloss combined with different colors.
Johne, Robert, Weingarten, Steven, Moritz, Tassilo, Hampel, Stefan, Scheithauer, Uwe, Cano, Santiago Cano, Abel, Johannes, Michaelis, Alexander, Cano, Santiago   +8 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Optimization of Mechanical Properties in Biomedical-Grade Polylactic Acid (PLA) Components Fabricated Via Fuzed Filament Fabrication (FFF)

Advances in Polymer Technology
The growing demand for personalized biomedical devices positions polylactic acid (PLA) as a useful material because it is biodegradable and biocompatible while being easily processed by additive manufacturing.
Sudheer Reddy, Muli Vaibhav Reddy, G. Vamsi Nivas, Abdulfatah Abdu Yusuf, Muhammad Imam Ammarullah   +4 more
doaj   +1 more source

Design and Characterization of 2.5D Nature-Inspired Infill Structures under Out-Plane Quasi-Static Loading Condition

Advances in Materials Science and Engineering, 2023
The 2.5D (2.5-dimensional) structures are acquired to enhance safety and lightweight designs with better energy absorption in the aerospace and automobile sectors. Additive manufacturing (AM), which is practical to build suitable components in industrial
Dara Ashok, M. V. A. Raju Bahubalendruni
doaj   +1 more source