Results 121 to 130 of about 123,217 (264)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Optimization of material and extrusion parameters for wood flour–epoxy composites with potential additive-manufacturing applications in construction [PDF]

Laura Vanessa Alvarez Marin, Zahra Naghizadeh, Tawsif Raman, María Soledad Peresin   +3 more
openalex   +1 more source

Life Cycle Assessment in Flange Part Production Comparing Wire and Arc Additive Manufacturing Method (WAAM) and Conventional Manufacturing in Terms of Energy Consumption, Greenhouse Gas Emissions and Solid Waste Generation

, 2023
Brunna Mothé Mattos, João da Cruz Payão Filho, Claudinei de Souza Guimarães   +2 more
openalex   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Isotropic High Strength Mg-Gd-Y-Zn-Zr Alloy Fabricated by Wire Arc Additive Manufacturing Based on Cold Metal Transfer

, 2023
Ze Deng, Qixin Su, Mengfan Chen, Fulin Wang, Linda Ke, Fenghua Wang, Jie Dong   +6 more
openalex   +1 more source

pH Monitoring: Probing the pH Microenvironment of Mesenchymal Stromal Cell Cultures on Additive‐Manufactured Scaffolds (Small 34/2020) [PDF]

, 2020
Ivan Lorenzo Moldero, Anil Chandra, Marta Cavo, Carlos Mota, Dimitrios Kapsokalyvas, Giuseppe Gigli, Lorenzo Moroni, Loretta L. del Mercato   +7 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Advances in Materials Joining and Additive Manufacturing. [PDF]

Materials (Basel)
Liu X, Shi L.
europepmc   +1 more source

Additive Manufacturing Impact on a Fluidic Oscillator with Respect to Surface Roughness

, 2022
Abdul Raouf Tajik, Vladimir Parezanović
openalex   +1 more source

A Review on the Functionality of Nanomaterials in 2d and 3d Additive Manufacturing [PDF]

, 2020
Markos Petousis
openalex   +1 more source