Results 51 to 60 of about 123,217 (264)

Compositional criteria to predict columnar to equiaxed transitions in metal additive manufacturing

Nature Communications
Predicting the columnar to equiaxed transition (CET) and grain refinement for additively manufactured alloys from thermodynamic databases has been a long-standing challenge and an ongoing source of discussion.
Ryan Brooke, Duyao Zhang, Dong Qiu, Mark A. Gibson, Mark Easton   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Effect of TiB₂ Addition on the Microstructure and Mechanical Properties of Laser-Directed Energy Deposition TiAl Alloy

Metals
The microstructure characteristics of TiAl alloy prepared by laser-directed energy deposition (L-DED) are coarse columnar grains parallel to the building direction, which results in serious mechanical properties and anisotropy and limits its application.
Yancheng Yang, Yi Hu, Hongyan Chen, Yu Li, Jiawei Wang, Xu Cheng, Haibo Tang, Xianzhe Ran, Dong Liu   +8 more
doaj   +1 more source

The Electric-Field-Driven Fusion Jetting 3D Printing for Fabricating High Resolution Polylactic Acid/Multi-Walled Carbon Nanotube Composite Micro-Scale Structures

Micromachines, 2020
Existing 3D printing techniques are still facing the challenge of low resolution for fabricating polymer matrix composites, inhibiting the wide engineering applications for the biomedical engineering (biomimetic scaffolds), micro fuel cells, and micro ...
Xiaoqiang Li, Guangming Zhang, Wenhai Li, Zun Yu, Kun Yang, Hongbo Lan   +5 more
doaj   +1 more source

3D Printing of a miniature turbine blade model with an embedded fibre Bragg grating sensor for high-temperature monitoring

Virtual and Physical Prototyping, 2022
Rapid advances in 3D printing enable the construction of complex metal structures. However, sensor embedding within 3D printed metal structures has been challenging due to its extremely high-temperature condition.
Seon Il Kim, Ho Yun Jung, Seungweon Yang, Jongcheon Yoon, Hyub Lee, WonHyoung Ryu   +5 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Optimization of Mechanical Properties in Biomedical-Grade Polylactic Acid (PLA) Components Fabricated Via Fuzed Filament Fabrication (FFF)

Advances in Polymer Technology
The growing demand for personalized biomedical devices positions polylactic acid (PLA) as a useful material because it is biodegradable and biocompatible while being easily processed by additive manufacturing.
Sudheer Reddy, Muli Vaibhav Reddy, G. Vamsi Nivas, Abdulfatah Abdu Yusuf, Muhammad Imam Ammarullah   +4 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Effect of fluoride ion cleaning on surface state and properties of Ni3Al-base superalloy IC10

Cailiao gongcheng
After turbine blades are in service， the defect surface oxide film will affect the repair quality of vacuum brazing. By cleaning the IC10 alloy with fluoride ion， the effects of fluoride ion cleaning on the removal of oxide film， the changes of surface ...
ZHOU Zizheng, ZHAO Haisheng, GAO Junjie, SUN Bingbing   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source