Results 41 to 50 of about 322,307 (338)
, 2006 A complete empirical approach from known Raman and IR spectra is used to make corrections to the bond additivity model for quantitative interpretation of Sum Frequency generation Vibrational Spectra (SFG-VS) from molecular interfaces.
Abbate S. +11 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Additivity property and emergence of power laws in nonequilibrium steady states
, 2015 We show that an equilibriumlike additivity property can remarkably lead to power-law distributions observed frequently in a wide class of out-of-equilibrium systems.
Chatterjee, Sayani +3 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Cooperative Games Based on Coalition Functions in Biform Games
Axioms, 2023 In this paper, we try to study a class of biform games with the coalition function from the cooperation of players. For this purpose, we interpret the biform games as cooperative games by defining a characteristic function of minimax representation based
Chenwei Liu +3 more
doaj +1 more source
Multicomplexes, bounded cohomology and additivity of simplicial volume
, 2015 We discuss some additivity properties of the simplicial volume for manifolds with boundary: we give proofs of additivity for glueing amenable boundary components and of superadditivity for glueing amenable submanifolds of the boundary, and we discuss ...
Kuessner, Thilo
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
On Hastings' counterexamples to the minimum output entropy additivity conjecture
, 2009 Hastings recently reported a randomized construction of channels violating the minimum output entropy additivity conjecture. Here we revisit his argument, presenting a simplified proof.
Amosov G. G. +8 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Green propolis as an adjuvant against nontuberculous mycobacteria
Rodriguésia, 2021 Natural products have been touted as important tools because of their vast potential for the development of compounds with antimicrobial activity and the possible inhibitory activity and/or adjuvant resistance mechanisms.
Suzane Olachea Allend +6 more
doaj +1 more source