Results 61 to 70 of about 35,641 (291)

Beyond medicine: A proof of concept for synergy analysis in ecotoxicology

Methods in Ecology and Evolution
Interactive effects among chemicals, such as synergism and antagonism, are increasingly studied in ecotoxicology and environmental research. However, these interactions are often assessed using a biased, point‐wise approach that overlooks dose‐dependent ...
Antoine Gekière, Maïlys Paulet, Lauralyne Paulet, Manon Fievet, Dimitri Evrard, Maxence Gérard   +5 more
doaj   +1 more source

The significance of value additivity

, 2022
Whether value is “additive,” that is, whether the value of a whole must equal the sum of the values of its parts, is widely thought to have significant implications in ethics.
Brown, Campbell
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Linkage Analysis and Association Mapping QTL Detection Models for Hybrids Between Multiparental Populations from Two Heterotic Groups: Application to Biomass Production in Maize (Zea mays L.)

G3: Genes, Genomes, Genetics, 2017
Identification of quantitative trait loci (QTL) involved in the variation of hybrid value is of key importance for cross-pollinated species such as maize (Zea mays L.).
Héloïse Giraud, Cyril Bauland, Matthieu Falque, Delphine Madur, Valérie Combes, Philippe Jamin, Cécile Monteil, Jacques Laborde, Carine Palaffre, Antoine Gaillard, Philippe Blanchard, Alain Charcosset, Laurence Moreau   +12 more
doaj   +1 more source

Binaural additivity of loudness

, 1972
A definition of binaural additivity is given in terms of the theory of simultaneous conjoint measurement. Additivity is then tested and verified by a conjoint measurement procedure.
A. A. Bunt, Riemersma, J.B., Bunt, A.A., W. J. M. Levelt, Levelt, W.J.M., J. B. Riemersma   +5 more
core   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Disjoint additivity and local quantum physics

Journal of High Energy Physics
Quantum systems of physical interest are often local, but there are at least three competing perspectives on how “locality” should be formalized: an algebraic framework, a path-integral framework, and a lattice framework.
Daniel Harlow, Shu-Heng Shao, Jonathan Sorce, Manu Srivastava   +3 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

The pig is an excellent model to determine amino acid digestibility of human foods and to generate data needed to meet human amino acid requirements

Frontiers in Nutrition
The protein value of any food item is determined by the quantity and ileal digestibility of indispensable amino acids in that food. To determine the ileal digestibility of amino acids, an animal model needs to be used, and the pig is the preferred model ...
Hans H. Stein
doaj   +1 more source

Tsallis Entropy and Generalized Shannon Additivity

Axioms, 2017
The Tsallis entropy given for a positive parameter α can be considered as a generalization of the classical Shannon entropy. For the latter, corresponding to α = 1 , there exist many axiomatic characterizations. One of them based on the well-
Sonja Jäckle, Karsten Keller
doaj   +1 more source